{"id":108428,"date":"2026-06-29T10:33:08","date_gmt":"2026-06-29T10:33:08","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/pyrokatechol-12-dihydroxybenzen\/"},"modified":"2026-06-29T10:33:08","modified_gmt":"2026-06-29T10:33:08","slug":"pyrokatechol-12-dihydroxybenzen","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/pyrokatechol-12-dihydroxybenzen\/","title":{"rendered":"Pyrokatechol (1,2-dihydroxybenzen)"},"content":{"rendered":"

Nejsou k dispozici \u017e\u00e1dn\u00e9 odhady aktu\u00e1ln\u00edho po\u010dtu pracovn\u00edk\u016f vystaven\u00fdch pyrokatecholu (1,2-dihydroxybenzenu) v EU.
\nPyrokatechol se pou\u017e\u00edv\u00e1 v pevn\u00e9 i kapaln\u00e9 form\u011b. Vzhledem k tomu, \u017ee m\u016f\u017ee pronikat k\u016f\u017e\u00ed, jsou relevantn\u00edmi cestami expozice jak vdechnut\u00ed, tak derm\u00e1ln\u00ed kontakt.
\nL\u00e1tka je podle CLP na\u0159\u00edzen\u00ed o klasifikaci ozna\u010dov\u00e1n\u00ed a balen\u00ed l\u00e1tek a sm\u011bs\u00ed klasifikov\u00e1na jako podez\u0159el\u00fd lidsk\u00fd karcinogen (kategorie 1B).<\/p>\n

Kde se vyskytuj\u00ed rizika<\/h2>\n

K pracovn\u00ed expozici pyrokatecholu doch\u00e1z\u00ed p\u0159edev\u0161\u00edm v chemick\u00e9 a farmaceutick\u00e9 v\u00fdrob\u011b, p\u0159i technick\u00e9m zkou\u0161en\u00ed a anal\u00fdze a v n\u011bkter\u00fdch navazuj\u00edc\u00edch odv\u011btv\u00edch, jako je povrchov\u00e1 \u00faprava, elektronika, v\u00fdroba pry\u017ee a plast\u016f a stroj\u00edrensk\u00e1 v\u00fdroba.
\nMezi profesion\u00e1ly s nejvy\u0161\u0161\u00edm rizikem expozice pyrokatecholu pat\u0159\u00ed oper\u00e1to\u0159i chemick\u00fdch proces\u016f, oper\u00e1to\u0159i destilace, m\u00edch\u00e1n\u00ed a skladovac\u00edch n\u00e1dr\u017e\u00ed, d\u00e1le pracovn\u00edci \u00fadr\u017eby, laboratorn\u00ed technici a analyti\u010dt\u00ed chemici. Exponov\u00e1ni mohou b\u00fdt tak\u00e9 pracovn\u00edci v galvanovn\u00e1ch a pracovn\u00edci zapojen\u00ed do povrchov\u00fdch \u00faprav a v\u00fdroby elektroniky.
\nExpozice je nejpravd\u011bpodobn\u011bj\u0161\u00ed p\u0159i \u010dinnostech, kde se s l\u00e1tkou manipuluje v otev\u0159en\u00fdch syst\u00e9mech nebo kde nen\u00ed izolace pln\u011b \u00fa\u010dinn\u00e1, jako je m\u00edch\u00e1n\u00ed nebo m\u00edsen\u00ed, p\u0159i m\u00e1\u010den\u00ed, lakov\u00e1n\u00ed nebo p\u0159i procesech povrchov\u00e9 \u00fapravy. K dal\u0161\u00ed expozici m\u016f\u017ee doj\u00edt b\u011bhem \u00fadr\u017eby a \u010di\u0161t\u011bn\u00ed.<\/p>\n

V\u00edce o l\u00e1tce<\/h2>\n

Pyrokatechol je p\u0159i pokojov\u00e9 teplot\u011b pevn\u00e1 l\u00e1tka, obvykle se objevuje jako b\u00edl\u00e1 a\u017e hn\u011bd\u00e1 krystalick\u00e1 l\u00e1tka, kter\u00e1 m\u016f\u017ee na vzduchu tmavnout. Pyrokatechol se velmi dob\u0159e rozpou\u0161t\u00ed ve vod\u011b a v mnoha organick\u00fdch rozpou\u0161t\u011bdlech.<\/p>\n

Pyrokatechol nen\u00ed za norm\u00e1ln\u00edch podm\u00ednek vysoce ho\u0159lav\u00fd ani v\u00fdbu\u0161n\u00fd. P\u0159i manipulaci v pevn\u00e9m stavu v\u0161ak m\u016f\u017ee tvo\u0159it prach a p\u0159i zah\u0159\u00edv\u00e1n\u00ed b\u011bhem pr\u016fmyslov\u00fdch proces\u016f nebo p\u0159i pou\u017eit\u00ed v kapaln\u00e9 form\u011b m\u016f\u017ee vytv\u00e1\u0159et aerosoly nebo p\u00e1ry.<\/p>\n

Pou\u017e\u00edv\u00e1 se hlavn\u011b jako meziprodukt p\u0159i v\u00fdrob\u011b jin\u00fdch l\u00e1tek a produkt\u016f. Mezi nejv\u011bt\u0161\u00ed kategorie produkt\u016f pro kone\u010dn\u00e9 pou\u017eit\u00ed pyrokatecholu pat\u0159\u00ed agrochemik\u00e1lie (p\u0159\u00edpravky na ochranu plodin), aromata a vonn\u00e9 l\u00e1tky (nap\u0159. vanilin, parf\u00e9movan\u00e9 v\u00fdrobky pro dom\u00e1cnost), farmaceutika a p\u0159\u00edsady do pry\u017ee\/polymer\u016f pro plasty, pneumatiky a pry\u017eov\u00e9 zbo\u017e\u00ed.<\/p>\n

Zdravotn\u00ed rizika, kter\u00e1 mohou nastat<\/h2>\n

K expozici pyrokatecholu m\u016f\u017ee doj\u00edt vdechnut\u00edm prachu nebo par a kontaktem s k\u016f\u017e\u00ed.
\nKr\u00e1tkodob\u00e1 expozice m\u016f\u017ee v\u00e9st k p\u0159\u00edznak\u016fm, jako je ka\u0161el, podr\u00e1\u017ed\u011bn\u00ed hrdla, podr\u00e1\u017ed\u011bn\u00ed o\u010d\u00ed a zarudnut\u00ed k\u016f\u017ee nebo nep\u0159\u00edjemn\u00e9 pocity. Velmi vysok\u00e9 expozice (nap\u0159\u00edklad p\u0159i po\u017eit\u00ed) mohou m\u00edt za n\u00e1sledek z\u00e1va\u017en\u011bj\u0161\u00ed toxick\u00e9 \u00fa\u010dinky. Po opakovan\u00e9 expozici m\u016f\u017ee tak\u00e9 zp\u016fsobit alergick\u00e9 ko\u017en\u00ed reakce.
\nDlouhodob\u00e1 expozice m\u016f\u017ee v\u00e9st k v\u00e1\u017en\u011bj\u0161\u00edm zdravotn\u00edm \u00fa\u010dink\u016fm, v\u010detn\u011b zv\u00fd\u0161en\u00e9ho rizika rakoviny, depigmentace k\u016f\u017ee, chronick\u00e9 dermatitidy a respira\u010dn\u00edch pot\u00ed\u017e\u00ed.<\/p>\n

Co m\u016f\u017ee\u0161 ud\u011blat<\/h2>\n

Prioritou by m\u011bla b\u00fdt substituce. Tam, kde je to mo\u017en\u00e9, by m\u011bl b\u00fdt pyrokatechol nahrazen m\u00e9n\u011b nebezpe\u010dn\u00fdmi l\u00e1tkami nebo alternativn\u00edmi procesy, kter\u00e9 sni\u017euj\u00ed expozici. Mo\u017en\u00e9 n\u00e1hrady za pyrokatechol (katechol) z\u00e1vis\u00ed na jeho roli: hydrochinon, resorcinol a pyrogallol jej mohou nahradit v n\u011bkter\u00fdch podobn\u00fdch chemick\u00fdch nebo redoxn\u00edch aplikac\u00edch; kyselina gallov\u00e1 nebo kyselina tannov\u00e1 mohou fungovat pro chelata\u010dn\u00ed \u00fa\u010dely; a kyselina askorbov\u00e1 nebo borohydrid sodn\u00fd mohou n\u011bkdy nahradit pyrokatechol jako reduk\u010dn\u00ed \u010dinidla. Nejlep\u0161\u00ed alternativa z\u00e1vis\u00ed na konkr\u00e9tn\u00ed aplikaci, proto\u017ee tyto slou\u010deniny maj\u00ed r\u016fznou reaktivitu.<\/p>\n

Technick\u00e1 opat\u0159en\u00ed jsou nezbytn\u00e1 tam, kde substituce nen\u00ed mo\u017en\u00e1. Pat\u0159\u00ed mezi n\u011b pou\u017e\u00edv\u00e1n\u00ed uzav\u0159en\u00fdch syst\u00e9m\u016f a automatizace, m\u00edstn\u00ed ods\u00e1v\u00e1n\u00ed v m\u00edstech emis\u00ed a \u00fa\u010dinn\u00e9 celkov\u00e9 v\u011btr\u00e1n\u00ed. Tato opat\u0159en\u00ed pom\u00e1haj\u00ed sni\u017eovat koncentraci par a prachu v ovzdu\u0161\u00ed.
\nOrganiza\u010dn\u00ed opat\u0159en\u00ed zahrnuj\u00ed omezen\u00ed doby expozice, poskytov\u00e1n\u00ed \u0161kolen\u00ed pracovn\u00edk\u016fm (nap\u0159\u00edklad o rizic\u00edch derm\u00e1ln\u00ed expozice), zav\u00e1d\u011bn\u00ed bezpe\u010dn\u00fdch postup\u016f manipulace a zaji\u0161t\u011bn\u00ed vhodn\u00fdch metod \u010di\u0161t\u011bn\u00ed, kter\u00e9 minimalizuj\u00ed tvorbu prachu. Doporu\u010duje se pravideln\u00e9 sledov\u00e1n\u00ed \u00farovn\u00ed expozice.<\/p>\n

Osobn\u00ed ochrana by m\u011bla b\u00fdt pou\u017e\u00edv\u00e1na jako posledn\u00ed mo\u017enost. Zvl\u00e1\u0161tn\u00ed pozornost by m\u011bla b\u00fdt v\u011bnov\u00e1na zamezen\u00ed kontaktu s k\u016f\u017e\u00ed, a to kv\u016fli schopnosti l\u00e1tky vst\u0159eb\u00e1vat se k\u016f\u017e\u00ed. To zahrnuje poskytov\u00e1n\u00ed vhodn\u00fdch chemicky odoln\u00fdch rukavic a od\u011bv\u016f (ochrann\u00fd od\u011bv s dlouh\u00fdmi ruk\u00e1vy a ochrana o\u010d\u00ed a obli\u010deje tam, kde hroz\u00ed post\u0159\u00edk\u00e1n\u00ed) a v p\u0159\u00edpad\u011b pot\u0159eby vybaven\u00ed pro ochranu d\u00fdchac\u00edch cest.<\/p>\n

Reference: ECHA, IARC, RAC<\/em><\/p>\n","protected":false},"template":"","carcinogens":[8679],"class_list":["post-108428","fact","type-fact","status-publish","hentry","carcinogens-pyrokatechol"],"yoast_head":"\nPyrokatechol (1,2-dihydroxybenzen) - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/pyrokatechol-12-dihydroxybenzen\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pyrokatechol (1,2-dihydroxybenzen)\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! 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