{"id":108433,"date":"2026-06-29T10:02:28","date_gmt":"2026-06-29T10:02:28","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/12-dichlorpropan\/"},"modified":"2026-06-29T10:02:28","modified_gmt":"2026-06-29T10:02:28","slug":"12-dichlorpropan","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/","title":{"rendered":"1,2-dichlorpropan"},"content":{"rendered":"

V EU nejsou k dispozici \u017e\u00e1dn\u00e9 odhady aktu\u00e1ln\u00edho po\u010dtu pracovn\u00edk\u016f vystaven\u00fdch 1,2-dichlorpropanu (1,2-DPC). Za prim\u00e1rn\u00ed cestu expozice se pova\u017euje vdechov\u00e1n\u00ed, a\u010dkoli pracovn\u00edci mohou b\u00fdt vystaveni i prost\u0159ednictv\u00edm derm\u00e1ln\u00edho kontaktu.<\/p><\/blockquote>\n

1,2-DPC je klasifikov\u00e1n jako karcinogen kategorie 1B (podle CLP na\u0159\u00edzen\u00ed o klasifikaci ozna\u010dov\u00e1n\u00ed a balen\u00ed l\u00e1tek a sm\u011bs\u00ed), co\u017e znamen\u00e1, \u017ee se na z\u00e1klad\u011b d\u016fkaz\u016f u zv\u00ed\u0159at p\u0159edpokl\u00e1d\u00e1 jeho karcinogenn\u00ed potenci\u00e1l pro \u010dlov\u011bka.<\/p>\n

Toxick\u00e9 \u00fa\u010dinky zahrnuj\u00ed po\u0161kozen\u00ed jater a ledvin, intravaskul\u00e1rn\u00ed koagulaci, hemolytickou anemii a r\u016fzn\u00e9 p\u0159\u00edznaky posti\u017een\u00ed centr\u00e1ln\u00edho nervov\u00e9ho syst\u00e9mu.<\/p>\n

Kde se rizika vyskytuj\u00ed<\/h2>\n

1,2-DCP je vedlej\u0161\u00ed produkt vznikaj\u00edc\u00ed ve v\u00fdznamn\u00e9m mno\u017estv\u00ed b\u011bhem v\u00fdrobn\u00edho procesu propylenoxidu chlorhydrinovou metodou za \u00fa\u010delem v\u00fdroby epichlorhydrinu. 1,2-DCP se historicky pou\u017e\u00edval jako p\u016fdn\u00ed fumigant, chemick\u00fd meziprodukt a tak\u00e9 jako pr\u016fmyslov\u00e9 rozpou\u0161t\u011bdlo. Vyskytoval se v odstra\u0148ova\u010d\u00edch n\u00e1t\u011br\u016f, lac\u00edch a odstra\u0148ova\u010d\u00edch povrchov\u00fdch \u00faprav n\u00e1bytku. Jako p\u016fdn\u00ed fumigant se ji\u017e nepou\u017e\u00edv\u00e1.<\/p>\n

V sou\u010dasn\u00e9 dob\u011b je jeho hlavn\u00edm vyu\u017eit\u00edm meziprodukt p\u0159i v\u00fdrob\u011b perchlorethylenu a dal\u0161\u00edch chlorovan\u00fdch chemik\u00e1li\u00ed.
\nObecn\u011b se zd\u00e1, \u017ee expozice na pracovi\u0161ti je omezen\u00e1 d\u00edky manipulaci za p\u0159\u00edsn\u011b kontrolovan\u00fdch podm\u00ednek. Hlavn\u00ed \u010dinnost\u00ed, p\u0159i kter\u00e9 je expozice mo\u017en\u00e1, je manu\u00e1ln\u00ed \u00fadr\u017eba nebo \u010di\u0161t\u011bn\u00ed.<\/p>\n

V\u00edce o l\u00e1tce<\/h2>\n

V \u010dist\u00e9 form\u011b je 1,2-DPC bezbarv\u00e1, ho\u0159lav\u00e1, pohybliv\u00e1 kapalina se z\u00e1pachem podobn\u00fdm chloroformu. Je m\u00edsiteln\u00fd s v\u011bt\u0161inou organick\u00fdch rozpou\u0161t\u011bdel, jako jsou alkoholy, estery a ketony, a tak\u00e9 s aromatick\u00fdmi, alifatick\u00fdmi a chlorovan\u00fdmi uhlovod\u00edky.
\nV sou\u010dasn\u00e9 dob\u011b se p\u0159ipravuje z\u00e1vazn\u00e1 limitn\u00ed hodnota expozice na pracovi\u0161ti pro celou EU.<\/p>\n

Rizika, kter\u00e1 mohou nastat<\/h2>\n

Kr\u00e1tkodob\u00e1 expozice 1,2-DCP u lid\u00ed m\u016f\u017ee po peror\u00e1ln\u00ed a derm\u00e1ln\u00ed absorpci zp\u016fsobit podr\u00e1\u017ed\u011bn\u00ed a tak\u00e9 dysfunkci jater a ledvin. P\u0159i velmi vysok\u00fdch koncentrac\u00edch byl hl\u00e1\u0161en \u00fatlum centr\u00e1ln\u00edho nervov\u00e9ho syst\u00e9mu.
\nP\u0159i dlouhodob\u00e9 expozici je nejkriti\u010dt\u011bj\u0161\u00edm \u00fa\u010dinkem u lid\u00ed karcinogenita, konkr\u00e9tn\u011b v\u00fdskyt n\u00e1dor\u016f \u017elu\u010dov\u00fdch cest (cholangiokarcinom).<\/p>\n

Co m\u016f\u017eete ud\u011blat<\/h2>\n

Na pracovi\u0161ti je nej\u00fa\u010dinn\u011bj\u0161\u00edm zp\u016fsobem prevence expozice n\u00e1hrada 1,2-DCP. Tam, kde n\u00e1hrada nen\u00ed mo\u017en\u00e1 a pou\u017eit\u00ed 1,2-DCP se nelze vyhnout, mus\u00ed b\u00fdt p\u0159ijata opat\u0159en\u00ed ke sn\u00ed\u017een\u00ed expozice.
\nNej\u00fa\u010dinn\u011bj\u0161\u00edm zp\u016fsobem, jak zabr\u00e1nit expozici 1,2-DCP, je v\u00fdvoj a pou\u017e\u00edv\u00e1n\u00ed uzav\u0159en\u00fdch syst\u00e9m\u016f. Pokud to nen\u00ed mo\u017en\u00e9, m\u011bla by b\u00fdt zavedena technick\u00e1 opat\u0159en\u00ed, jako je \u00fa\u010dinn\u00e9 m\u00edstn\u00ed ods\u00e1v\u00e1n\u00ed, dopln\u011bn\u00e9 dobr\u00fdm celkov\u00fdm v\u011btr\u00e1n\u00edm pracovi\u0161t\u011b a pravideln\u00fdmi kontrolami jejich \u00fa\u010dinnosti, aby se zajistilo, \u017ee expozice bude minimalizov\u00e1na na technicky nejni\u017e\u0161\u00ed mo\u017enou m\u00edru.<\/p>\n

Ve\u0161ker\u00e1 v\u00fdroba 1,2-DPC prob\u00edh\u00e1 v uzav\u0159en\u00fdch syst\u00e9mech. K expozici doch\u00e1z\u00ed p\u0159i otev\u0159en\u00ed t\u011bchto uzav\u0159en\u00fdch syst\u00e9m\u016f za \u00fa\u010delem b\u011b\u017en\u00e9 \u00fadr\u017eby, kontroly nebo \u010di\u0161t\u011bn\u00ed. V t\u011bchto p\u0159\u00edpadech je nutn\u00e9 pou\u017e\u00edvat technick\u00e1 opat\u0159en\u00ed a Osobn\u00ed ochrana, v\u010detn\u011b prost\u0159edk\u016f na ochranu d\u00fdchac\u00edch cest.<\/p>\n

Zave\u010fte opat\u0159en\u00ed k zaji\u0161t\u011bn\u00ed \u0159\u00e1dn\u00e9 celkov\u00e9 hygieny na pracovi\u0161ti s pravideln\u00fdm \u00faklidem a hygienick\u00fdm skladov\u00e1n\u00edm. Po po\u010d\u00e1te\u010dn\u00edm m\u011b\u0159en\u00ed expozice pro hodnocen\u00ed rizik prov\u00e1d\u011bjte pravideln\u00e9 hodnocen\u00ed expozice, abyste zkontrolovali, zda jsou zaveden\u00e1 technick\u00e1 opat\u0159en\u00ed \u00fa\u010dinn\u00e1 nebo zda je t\u0159eba p\u0159ijmout dal\u0161\u00ed opat\u0159en\u00ed. D\u016fle\u017eit\u00fdmi opat\u0159en\u00edmi ke sn\u00ed\u017een\u00ed expozice jsou p\u0159\u00edsn\u00e9 omezen\u00ed doby, kterou pracovn\u00edk tr\u00e1v\u00ed v exponovan\u00e9m pracovn\u00edm prost\u0159ed\u00ed (nap\u0159. prost\u0159ednictv\u00edm sm\u011bn), a omezen\u00ed p\u0159\u00edstupu na tato pracovi\u0161t\u011b. Zam\u011bstnanec mus\u00ed b\u00fdt informov\u00e1n o mo\u017en\u00fdch rizic\u00edch spojen\u00fdch s \u00fakoly zahrnuj\u00edc\u00edmi 1,2-DPC a zam\u011bstnavatel\u00e9 je mus\u00ed pravideln\u011b \u0161kolit a instruovat o tom, jak s 1,2-DPC bezpe\u010dn\u011b pracovat.<\/p>\n

U pracovn\u00edk\u016f vystaven\u00fdch nebezpe\u010dn\u00fdm l\u00e1tk\u00e1m je vy\u017eadov\u00e1n l\u00e9ka\u0159sk\u00fd dohled a v souladu s t\u00edm by m\u011bli b\u00fdt povzbuzov\u00e1ni k hl\u00e1\u0161en\u00ed \u010dasn\u00fdch p\u0159\u00edznak\u016f, jako jsou respira\u010dn\u00ed probl\u00e9my nebo ko\u017en\u00ed alergie.
\nKrom\u011b toho \u0161kolte pracovn\u00edky o v\u00fdznamu \u00fa\u010dinn\u00e9 osobn\u00ed hygieny. Zajist\u011bte odpov\u00eddaj\u00edc\u00ed um\u00fdv\u00e1rny a toalety a poskytn\u011bte pracovn\u00edk\u016fm dostatek \u010dasu na hygienick\u00e1 opat\u0159en\u00ed.<\/p>\n

Zajist\u011bte, aby pracovn\u00edci m\u011bli v p\u0159\u00edpad\u011b pot\u0159eby odpov\u00eddaj\u00edc\u00ed Osobn\u00ed ochrana, jako je ochrann\u00fd od\u011bv a rukavice. Osobn\u00ed ochrana by m\u011bla b\u00fdt pou\u017e\u00edv\u00e1na pouze jako posledn\u00ed mo\u017enost a zva\u017eov\u00e1na pouze do\u010dasn\u011b, po vy\u010derp\u00e1n\u00ed mo\u017en\u00fdch technick\u00fdch a organiza\u010dn\u00edch \u0159e\u0161en\u00ed.<\/p>\n

Reference: ECHA, ATSDR 2021<\/em><\/p>\n","protected":false},"template":"","carcinogens":[8680],"class_list":["post-108433","fact","type-fact","status-publish","hentry","carcinogens-12-dichlorpropan"],"yoast_head":"\n1,2-dichlorpropan - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"1,2-dichlorpropan\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/\" \/>\n<meta property=\"og:site_name\" content=\"STOP carcinogens at work\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Odhadovan\u00e1 doba \u010dten\u00ed \" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minuta\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/fact\\\/12-dichlorpropan\\\/\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/fact\\\/12-dichlorpropan\\\/\",\"name\":\"1,2-dichlorpropan - STOP carcinogens at work\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/#website\"},\"datePublished\":\"2026-06-29T10:02:28+00:00\",\"description\":\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/fact\\\/12-dichlorpropan\\\/#breadcrumb\"},\"inLanguage\":\"cs-CZ\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/fact\\\/12-dichlorpropan\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/fact\\\/12-dichlorpropan\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/stop-karcinogenum-pri-praci\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Facts\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/fact\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"1,2-dichlorpropan\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/#website\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/\",\"name\":\"STOP Carcinogens at work\",\"description\":\"Every year, about 100.000 people die from cancer that was caused by exposure to carcinogens at work in Europe.\",\"publisher\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/#organization\"},\"alternateName\":\"Roadmap on Carcinogens\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"cs-CZ\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/#organization\",\"name\":\"TNO\",\"alternateName\":\"This is a European wide voluntary action scheme\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"cs-CZ\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/cropped-FavLarge-1.png\",\"contentUrl\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/cropped-FavLarge-1.png\",\"width\":512,\"height\":512,\"caption\":\"TNO\"},\"image\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/cs\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"publishingPrinciples\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/legal\\\/\",\"ownershipFundingInfo\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/general\\\/about-us\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"1,2-dichlorpropan - STOP carcinogens at work","description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/","og_locale":"cs_CZ","og_type":"article","og_title":"1,2-dichlorpropan","og_description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","og_url":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/","og_site_name":"STOP carcinogens at work","twitter_card":"summary_large_image","twitter_misc":{"Odhadovan\u00e1 doba \u010dten\u00ed ":"4 minuta"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/","url":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/","name":"1,2-dichlorpropan - STOP carcinogens at work","isPartOf":{"@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/#website"},"datePublished":"2026-06-29T10:02:28+00:00","description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","breadcrumb":{"@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/#breadcrumb"},"inLanguage":"cs-CZ","potentialAction":[{"@type":"ReadAction","target":["https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/12-dichlorpropan\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/stopcarcinogensatwork.eu\/cs\/stop-karcinogenum-pri-praci\/"},{"@type":"ListItem","position":2,"name":"Facts","item":"https:\/\/stopcarcinogensatwork.eu\/cs\/fact\/"},{"@type":"ListItem","position":3,"name":"1,2-dichlorpropan"}]},{"@type":"WebSite","@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/#website","url":"https:\/\/stopcarcinogensatwork.eu\/cs\/","name":"STOP Carcinogens at work","description":"Every year, about 100.000 people die from cancer that was caused by exposure to carcinogens at work in Europe.","publisher":{"@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/#organization"},"alternateName":"Roadmap on Carcinogens","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/stopcarcinogensatwork.eu\/cs\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"cs-CZ"},{"@type":"Organization","@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/#organization","name":"TNO","alternateName":"This is a European wide voluntary action scheme","url":"https:\/\/stopcarcinogensatwork.eu\/cs\/","logo":{"@type":"ImageObject","inLanguage":"cs-CZ","@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/#\/schema\/logo\/image\/","url":"https:\/\/stopcarcinogensatwork.eu\/wp-content\/uploads\/2024\/08\/cropped-FavLarge-1.png","contentUrl":"https:\/\/stopcarcinogensatwork.eu\/wp-content\/uploads\/2024\/08\/cropped-FavLarge-1.png","width":512,"height":512,"caption":"TNO"},"image":{"@id":"https:\/\/stopcarcinogensatwork.eu\/cs\/#\/schema\/logo\/image\/"},"publishingPrinciples":"https:\/\/stopcarcinogensatwork.eu\/legal\/","ownershipFundingInfo":"https:\/\/stopcarcinogensatwork.eu\/general\/about-us\/"}]}},"_links":{"self":[{"href":"https:\/\/stopcarcinogensatwork.eu\/cs\/wp-json\/wp\/v2\/fact\/108433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stopcarcinogensatwork.eu\/cs\/wp-json\/wp\/v2\/fact"}],"about":[{"href":"https:\/\/stopcarcinogensatwork.eu\/cs\/wp-json\/wp\/v2\/types\/fact"}],"wp:attachment":[{"href":"https:\/\/stopcarcinogensatwork.eu\/cs\/wp-json\/wp\/v2\/media?parent=108433"}],"wp:term":[{"taxonomy":"carcinogens","embeddable":true,"href":"https:\/\/stopcarcinogensatwork.eu\/cs\/wp-json\/wp\/v2\/carcinogens?post=108433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}