{"id":76893,"date":"2023-08-29T10:09:26","date_gmt":"2023-08-29T10:09:26","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/isopren\/"},"modified":"2026-06-13T11:27:47","modified_gmt":"2026-06-13T11:27:47","slug":"isopren","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/isopren\/","title":{"rendered":"Isopren"},"content":{"rendered":"

Det ansl\u00e5s, at 10.539 arbejdere i EU kan v\u00e6re udsat for Isopren. P\u00e5 arbejdspladser, hvor Isopren fremstilles eller anvendes, kan eksponering prim\u00e6rt ske gennem ind\u00e5nding af dampe og gennem hudkontakt, men optagelse gennem huden anses for at v\u00e6re ubetydelig. If\u00f8lge CLP er Isopren klassificeret som carcinogen i kategori 1B (H350: Kan for\u00e5rsage kr\u00e6ft). Kronisk og h\u00f8j eksponering kan f\u00f8re til leverkr\u00e6ft som den prim\u00e6re virkning, men ogs\u00e5 an\u00e6mi, degeneration af det olfaktoriske epitel (v\u00e6vet inde i n\u00e6sehulen, der er involveret i lugtperception) og degeneration af rygmarvens hvide substans. <\/p><\/blockquote>\n

Hvor risici opst\u00e5r<\/h2>\n

Isopren anvendes som monomer i fremstilling og forarbejdning af polymerer. Desuden anvendes det som mellemprodukt i syntesen af kemiske stoffer. Der kan ogs\u00e5 forekomme eksponering under fremstillingen af isopren eller n\u00e5r det anvendes som b\u00e6redygtigt flybr\u00e6ndstof. Arbejdere inden for fremstilling af kemikalier og kemiske produkter samt fremstilling af plast- og gummiprodukter er udsat for risiko for eksponering. <\/p>\n

Mere om stoffet<\/h2>\n

Isopren er en farvel\u00f8s, brandfarlig v\u00e6ske med en svag lugt. Det har et lavt kogepunkt p\u00e5 kun 34 \u00b0C og dermed et ekstremt h\u00f8jt damptryk p\u00e5 634 hPa allerede ved 21,1 \u00b0C. Det betyder, at det fordamper hurtigt ved stuetemperatur. De frigivne dampe kan ind\u00e5ndes eller skabe en eksplosiv atmosf\u00e6re. Isopren er et metabolit, der forekommer naturligt i mange planter, dyr og mennesker. Isopren udskilles af mange tr\u00e6arter i store m\u00e6ngder (men nedbrydes hurtigt, hvilket betyder, at koncentrationerne i milj\u00f8et er lave) og kan ogs\u00e5 p\u00e5vises i menneskers \u00e5nde. Isopren er i sig selv ikke genotoksisk, men metaboliseres let til et genotoksisk mono- og diepoxid, hovedsageligt i leveren. Isoprenpolymerer er hovedbestanddelen i naturgummi. De mest almindelige produkter fremstillet af isopren er d\u00e6k. <\/p>\n

Farer, der kan opst\u00e5<\/h2>\n

Det st\u00f8rste potentiale for erhvervsm\u00e6ssig eksponering for isopren er ved ind\u00e5nding af dampe. En enkelt eller kortvarig eksponering for isopren kan for\u00e5rsage irritation af n\u00e6se, hals og lunger og kan f\u00f8re til hovedpine eller svimmelhed. Mens den akutte toksicitet er lav (dvs. det er meget usandsynligt at d\u00f8 af en enkelt kortvarig eksponering), er langvarig eller gentagen eksponering for isopren forbundet med leverkr\u00e6ft, degeneration af lugteepitelet og degeneration af rygmarvens hvide substans. <\/p>\n

For leverkr\u00e6ft ansl\u00e5s latenstiden til at v\u00e6re 18 \u00e5r.<\/strong><\/p>\n

Hvad du kan g\u00f8re<\/h2>\n

Den mest effektive m\u00e5de at forebygge eksponering p\u00e5 er at erstatte isopren med mere sikre alternativer. Hvor substitution af isopren ikke er mulig, og brugen af isopren ikke kan undg\u00e5s, skal der tr\u00e6ffes foranstaltninger til at reducere eksponeringen. I sektoren for fremstilling af raffinerede olieprodukter, som er ansvarlig for produktionen og ikke brugen af isopren, er substitution ikke relevant. Brug af andre monomerer i gummiindustrien kan dog v\u00e6re en mulighed. Den n\u00e6stmest effektive m\u00e5de at undg\u00e5 eksponering for isopren p\u00e5 er at udvikle og bruge lukkede systemer. Lukkede systemer er almindeligt forekommende p\u00e5 tv\u00e6rs af alle produktionsprocesser i b\u00e5de raffinering og polymerisering af isopren. <\/p>\n

Hvis det ikke er muligt at undg\u00e5 brugen af stoffet eller anvende en lukket proces, b\u00f8r der iv\u00e6rks\u00e6ttes tekniske foranstaltninger, s\u00e5som effektiv lokal udsugning eller god ventilation p\u00e5 arbejdspladsen, samt kontrol af disse foranstaltningers effektivitet, for at sikre, at eksponeringen minimeres s\u00e5 meget som teknisk muligt. Isopren forarbejdes ofte i trykregulerede kabiner, som er meget effektive til at reducere fordampningen. <\/p>\n

Gennemf\u00f8r regelm\u00e6ssige eksponeringsvurderinger for at kontrollere, om dine beskyttelsesforanstaltninger er effektive, eller om der skal tr\u00e6ffes yderligere foranstaltninger. Arbejderne skal v\u00e6re opm\u00e6rksomme p\u00e5 virkningerne af eksponering og b\u00f8r regelm\u00e6ssigt uddannes i de kontrolforanstaltninger, der er n\u00f8dvendige for at arbejde sikkert med Isopren for at forhindre eksponering. De b\u00f8r opfordres til at rapportere symptomer som irritation af n\u00e6se, hals og lunger (f.eks. hoste og hv\u00e6sende vejrtr\u00e6kning), hovedpine eller svimmelhed, da de kan v\u00e6re tegn p\u00e5, at de eksisterende foranstaltninger ikke er tilstr\u00e6kkelige. Det anbefales at inddrage en arbejdsmediciner. <\/p>\n

Derudover b\u00f8r man uddanne togarbejdere i effektive hygiejneforanstaltninger.<\/p>\n

S\u00f8rg for, at arbejderne har passende udstyr til personlig beskyttelse (PPE), s\u00e5som beskyttelsest\u00f8j og handsker, hvis det er n\u00f8dvendigt. Hvis der anvendes genanvendeligt PPE, skal man s\u00f8rge for, at det reng\u00f8res eller udskiftes, hvis det er n\u00f8dvendigt, og opbevares p\u00e5 et rent sted. Ved Isopren er der ofte behov for \u00e5ndedr\u00e6tsv\u00e6rn samt beskyttelseshandsker og beskyttelsesbriller. Hvis der er behov for \u00e5ndedr\u00e6tsv\u00e6rn, skal du sikre, at vejrtr\u00e6kningen ikke bliver yderligere fysisk belastende. Personlig beskyttelse b\u00f8r kun anvendes som en sidste udvej og kun betragtes som en midlertidig l\u00f8sning, efter at de mulige tekniske l\u00f8sninger er udt\u00f8mt. <\/p>\n

Referencer: ECHA, RAC, DG EMPL<\/em><\/p>\n","protected":false},"template":"","carcinogens":[4093],"class_list":["post-76893","fact","type-fact","status-publish","hentry","carcinogens-isopren-da"],"yoast_head":"\nIsopren - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Det ansl\u00e5s, at 10.539 arbejdere i EU kan v\u00e6re udsat for Isopren. Uds\u00e6ttelse kan medf\u00f8re leverkr\u00e6ft som den prim\u00e6re helbredsm\u00e6ssige konsekvens.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/isopren\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Isopren\" \/>\n<meta property=\"og:description\" content=\"Det ansl\u00e5s, at 10.539 arbejdere i EU kan v\u00e6re udsat for Isopren. 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