{"id":76907,"date":"2024-01-04T09:27:50","date_gmt":"2024-01-04T09:27:50","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/o-toluidin\/"},"modified":"2026-06-30T13:05:27","modified_gmt":"2026-06-30T13:05:27","slug":"o-toluidin","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/","title":{"rendered":"o-Toluidin"},"content":{"rendered":"

Der foreligger ingen sk\u00f8n over det aktuelle antal arbejder, der er udsat for ortho-toluidin (o-Toluidin) i EU. I 2011 blev det p\u00e5 baggrund af data fra 2006\/2007 ansl\u00e5et, at 5 500 arbejdere var udsat, hvoraf 3 100 var besk\u00e6ftiget inden for fremstilling af kemikalier og kemiske produkter eller fremstilling af gummiprodukter. <\/p><\/blockquote>\n

Uds\u00e6ttelse sker hovedsageligt gennem ind\u00e5nding og optagelse gennem huden; der kr\u00e6ves ingen direkte hudkontakt. Der kan ogs\u00e5 forekomme optagelse ved indtagelse og ved kontakt med \u00f8jnene. <\/p>\n

o-Toluidin er klassificeret som et harmoniseret stof i henhold til CLP-forordningen i carcinogen kategori 1B (formodet carcinogen potentiale hos mennesker, hovedsageligt baseret p\u00e5 resultater fra fors\u00f8g med dyr). Hos mennesker kan o-Toluidin for\u00e5rsage bl\u00e6rekr\u00e6ft. Optagelse gennem huden kan bidrage til den samlede belastning af kroppen. <\/p>\n

Hvor risici opst\u00e5r<\/h2>\n

Eksponeringen for o-Toluidin har historisk set v\u00e6ret langt h\u00f8jere, men kan stadig forekomme i dag i flere arbejdsmilj\u00f8er, is\u00e6r i den kemiske industri under fremstilling, forarbejdning, pr\u00f8veudtagning eller h\u00e5ndtering af o-Toluidin eller ved anvendelse heraf som mellemprodukt, is\u00e6r i farvestofproduktion og ved fremstilling af plantebeskyttelsesmidler. Andre eksponeringssituationer kan opst\u00e5 som f\u00f8lge af frigivelse fra azofarvestoffer eller farvestoffer, der anvendes i tekstiler, trykfarver, plast, sm\u00f8remidler og mineralolieprodukter; frigivelse fra tils\u00e6tningsstoffer under termiske processer s\u00e5som vulkanisering; termisk nedbrydning af organiske bindemidler, is\u00e6r i st\u00f8beprocesser; h\u00e5ndtering eller opvarmning af materialer, der indeholder stenkulstj\u00e6re; samt laboratorie- og forskningsaktiviteter. <\/p>\n

Mere om stoffet<\/h2>\n

o-Toluidin fremstilles industrielt ved nitrering af Toluen, hvilket giver en blanding af nitrotoluener; det er den vigtigste af de tre isomere toluidiner. Det er en farvel\u00f8s v\u00e6ske, selvom kommercielle pr\u00f8ver ofte er gullige. o-Toluidin er et mellemprodukt i den biologiske nedbrydning af o-nitrotoluen og p\u00e5vises derfor p\u00e5 tidligere ammunitionsdepoter. o-Toluidin dannes under pyrolyse.
\nDer kendes ingen direkte forbrugeranvendelse af o-toluidin, da det er forbudt i kosmetik i henhold til EU’s kosmetikforordning. Anvendelsen af azofarvestoffer, der frigiver o-Toluidin under nedbrydning, er ikke tilladt i tekstiler og andre forbrugsartikler i EU. Eksponeringen af forbrugere og milj\u00f8et som f\u00f8lge af udledninger fra forbrugerprodukter synes derfor at v\u00e6re ubetydelig. <\/p>\n

For o-Toluidin g\u00e6lder der en EU-d\u00e6kkende, bindende gr\u00e6nsev\u00e6rdi for erhvervsm\u00e6ssig eksponering p\u00e5 0,5 mg\/m\u00b3 i luften.<\/p>\n

Sundhedsrisici, der kan opst\u00e5<\/h2>\n

o-Toluidin optages godt ved ind\u00e5nding og gennem huden. Oral eksponering er ikke relevant p\u00e5 arbejdspladsen.
\nDer foreligger ingen rapporter om virkninger efter akut eksponering, men p\u00e5 baggrund af data fra dyrefors\u00f8g antages der at v\u00e6re en akut irriterende virkning p\u00e5 \u00f8jne og hud. <\/p>\n

Bl\u00e6rekr\u00e6ft betragtes som den relevante sundhedsm\u00e6ssige virkning hos mennesker. I nogle medlemsstater er dette en anerkendt erhvervssygdom, der er forbundet med tidligere eksponering for o-Toluidin. <\/p>\n

Latensperioden mellem eksponering og udbrud af o-Toluidin-relateret bl\u00e6rekr\u00e6ft varierer meget, men anses typisk for at ligge mellem 15 og 40 \u00e5r.<\/strong><\/p>\n

Hvad du kan g\u00f8re<\/h2>\n

Erstatning b\u00f8r overvejes i anvendelser, hvor det er muligt. For at undg\u00e5 skadelige sundhedsm\u00e6ssige virkninger er det af allerst\u00f8rste betydning at reducere eksponeringen til under den bindende gr\u00e6nsev\u00e6rdi for erhvervsm\u00e6ssig eksponering eller den sundhedsbaserede gr\u00e6nsev\u00e6rdi. I industrielle processer er eksempler p\u00e5 tekniske kontrolforanstaltninger lukkede systemer, generel udsugning og lokal udsugning. Selv ved arbejde med lukkede systemer kan der forekomme eksponering, f.eks. under pr\u00f8veudtagning eller vedligeholdelse. Her er m\u00e5linger og kontrolforanstaltninger relevante. Andre anbefalede arbejdsmetoder omfatter at give medarbejderne information om farerne og uddannelse samt generelle standarder for arbejdshygiejne i omr\u00e5der, hvor der h\u00e5ndteres kemikalier. Medarbejdere, der udf\u00f8rer vedligeholdelse og reng\u00f8ring, b\u00f8r ligeledes uddannes. Det anbefales at inddrage en arbejdsmediciner. V\u00e6r opm\u00e6rksom p\u00e5, at eksponeringsvurderingen b\u00f8r underst\u00f8ttes af biomonitorering, hvis dette er relevant i henhold til national lovgivning, da o-Toluidin absorberes godt gennem huden. Arbejdere skal v\u00e6re opm\u00e6rksomme p\u00e5 virkningerne af eksponering. Personlig beskyttelse b\u00f8r kun anvendes som en sidste udvej, efter at de mulige tekniske l\u00f8sninger er indf\u00f8rt. <\/p>\n

Kilder: ECHA, IOM, SCOEL<\/p>\n","protected":false},"template":"","carcinogens":[4090],"class_list":["post-76907","fact","type-fact","status-publish","hentry","carcinogens-o-toluidin-da"],"yoast_head":"\no-Toluidin - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"o-Toluidin\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/\" \/>\n<meta property=\"og:site_name\" content=\"STOP carcinogens at work\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-30T13:05:27+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimeret l\u00e6setid\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutter\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/fact\\\/o-toluidin\\\/\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/fact\\\/o-toluidin\\\/\",\"name\":\"o-Toluidin - STOP carcinogens at work\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/#website\"},\"datePublished\":\"2024-01-04T09:27:50+00:00\",\"dateModified\":\"2026-06-30T13:05:27+00:00\",\"description\":\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/fact\\\/o-toluidin\\\/#breadcrumb\"},\"inLanguage\":\"da-DK\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/fact\\\/o-toluidin\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/fact\\\/o-toluidin\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Facts\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/fact\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Alle kr\u00e6ftfremkaldende stoffer\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/carcinogens\\\/alle-kraeftfremkaldende-stoffer\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"o-Toluidin\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/carcinogens\\\/o-toluidin-da\\\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"o-Toluidin\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/#website\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/\",\"name\":\"STOP Carcinogens at work\",\"description\":\"Every year, about 100.000 people die from cancer that was caused by exposure to carcinogens at work in Europe.\",\"publisher\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/#organization\"},\"alternateName\":\"Roadmap on Carcinogens\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"da-DK\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/#organization\",\"name\":\"TNO\",\"alternateName\":\"This is a European wide voluntary action scheme\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"da-DK\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/cropped-FavLarge-1.png\",\"contentUrl\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/cropped-FavLarge-1.png\",\"width\":512,\"height\":512,\"caption\":\"TNO\"},\"image\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/da\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"publishingPrinciples\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/homepage\\\/legal\\\/\",\"ownershipFundingInfo\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/general\\\/about-us\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"o-Toluidin - STOP carcinogens at work","description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/","og_locale":"da_DK","og_type":"article","og_title":"o-Toluidin","og_description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","og_url":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/","og_site_name":"STOP carcinogens at work","article_modified_time":"2026-06-30T13:05:27+00:00","twitter_card":"summary_large_image","twitter_misc":{"Estimeret l\u00e6setid":"3 minutter"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/","url":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/","name":"o-Toluidin - STOP carcinogens at work","isPartOf":{"@id":"https:\/\/stopcarcinogensatwork.eu\/da\/#website"},"datePublished":"2024-01-04T09:27:50+00:00","dateModified":"2026-06-30T13:05:27+00:00","description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","breadcrumb":{"@id":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/#breadcrumb"},"inLanguage":"da-DK","potentialAction":[{"@type":"ReadAction","target":["https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/o-toluidin\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/stopcarcinogensatwork.eu\/da\/"},{"@type":"ListItem","position":2,"name":"Facts","item":"https:\/\/stopcarcinogensatwork.eu\/da\/fact\/"},{"@type":"ListItem","position":3,"name":"Alle kr\u00e6ftfremkaldende stoffer","item":"https:\/\/stopcarcinogensatwork.eu\/da\/carcinogens\/alle-kraeftfremkaldende-stoffer\/"},{"@type":"ListItem","position":4,"name":"o-Toluidin","item":"https:\/\/stopcarcinogensatwork.eu\/da\/carcinogens\/o-toluidin-da\/"},{"@type":"ListItem","position":5,"name":"o-Toluidin"}]},{"@type":"WebSite","@id":"https:\/\/stopcarcinogensatwork.eu\/da\/#website","url":"https:\/\/stopcarcinogensatwork.eu\/da\/","name":"STOP Carcinogens at work","description":"Every year, about 100.000 people die from cancer that was caused by exposure to carcinogens at work in Europe.","publisher":{"@id":"https:\/\/stopcarcinogensatwork.eu\/da\/#organization"},"alternateName":"Roadmap on Carcinogens","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/stopcarcinogensatwork.eu\/da\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"da-DK"},{"@type":"Organization","@id":"https:\/\/stopcarcinogensatwork.eu\/da\/#organization","name":"TNO","alternateName":"This is a European wide voluntary action scheme","url":"https:\/\/stopcarcinogensatwork.eu\/da\/","logo":{"@type":"ImageObject","inLanguage":"da-DK","@id":"https:\/\/stopcarcinogensatwork.eu\/da\/#\/schema\/logo\/image\/","url":"https:\/\/stopcarcinogensatwork.eu\/wp-content\/uploads\/2024\/08\/cropped-FavLarge-1.png","contentUrl":"https:\/\/stopcarcinogensatwork.eu\/wp-content\/uploads\/2024\/08\/cropped-FavLarge-1.png","width":512,"height":512,"caption":"TNO"},"image":{"@id":"https:\/\/stopcarcinogensatwork.eu\/da\/#\/schema\/logo\/image\/"},"publishingPrinciples":"https:\/\/stopcarcinogensatwork.eu\/homepage\/legal\/","ownershipFundingInfo":"https:\/\/stopcarcinogensatwork.eu\/general\/about-us\/"}]}},"_links":{"self":[{"href":"https:\/\/stopcarcinogensatwork.eu\/da\/wp-json\/wp\/v2\/fact\/76907","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stopcarcinogensatwork.eu\/da\/wp-json\/wp\/v2\/fact"}],"about":[{"href":"https:\/\/stopcarcinogensatwork.eu\/da\/wp-json\/wp\/v2\/types\/fact"}],"wp:attachment":[{"href":"https:\/\/stopcarcinogensatwork.eu\/da\/wp-json\/wp\/v2\/media?parent=76907"}],"wp:term":[{"taxonomy":"carcinogens","embeddable":true,"href":"https:\/\/stopcarcinogensatwork.eu\/da\/wp-json\/wp\/v2\/carcinogens?post=76907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}