{"id":106440,"date":"2026-06-29T10:02:28","date_gmt":"2026-06-29T10:02:28","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/12-dikloropropan\/"},"modified":"2026-06-29T10:02:28","modified_gmt":"2026-06-29T10:02:28","slug":"12-dikloropropan","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/hr\/fact\/12-dikloropropan\/","title":{"rendered":"1,2-dikloropropan"},"content":{"rendered":"

Nema procjena trenutnog broja radnika izlo\u017eenih 1,2-dikloropropanu (1,2-DPC) u EU. Udisanje se smatra primarnim putem izlo\u017eenosti, iako radnici mogu biti izlo\u017eeni i putem kontakta s ko\u017eom. <\/p><\/blockquote>\n

1,2-DPC je klasificiran kao karcinogeni spoj kategorije 1B (prema CLP uredbi), \u0161to zna\u010di da se pretpostavlja da ima karcinogeni potencijal za ljude, na temelju dokaza na \u017eivotinjama.<\/p>\n

Toksi\u010dni u\u010dinci uklju\u010divali su o\u0161te\u0107enje jetre i bubrega, intravaskularnu koagulaciju, hemoliti\u010dku anemiju i razne simptome sredi\u0161njeg \u017eiv\u010danog sustava.<\/p>\n

Gdje se javljaju rizici<\/h2>\n

1,2-DCP je nusproizvod koji se proizvodi u zna\u010dajnim koli\u010dinama tijekom procesa proizvodnje propilen oksida klorohidrinskim postupkom za proizvodnju epiklorohidrina. 1,2-DCP se tradicionalno koristio kao fumigant tla, kemijski me\u0111uprodukt, kao i industrijsko otapalo. Nalazio se u sredstvima za odstranjivanje boje, lakovima i sredstvima za uklanjanje premaza s namje\u0161taja. Vi\u0161e se ne koristi kao fumigant tla. <\/p>\n

Trenutno se koristi kao me\u0111uprodukt u proizvodnji perkloretilena i drugih kloriranih kemikalija.
\n Op\u0107enito, izlo\u017eenost na radnom mjestu \u010dini se ograni\u010denom zbog rukovanja u strogo kontroliranim uvjetima. Glavna aktivnost u kojoj je mogu\u0107a izlo\u017eenost je tijekom ru\u010dnog odr\u017eavanja ili \u010di\u0161\u0107enja. <\/p>\n

Vi\u0161e o supstanci<\/h2>\n

U svom \u010distom obliku, 1,2-DPC je bezbojna, zapaljiva, pokretna teku\u0107ina s mirisom sli\u010dnim kloroformu. Mije\u0161a se s ve\u0107inom organskih otapala, kao \u0161to su alkoholi, esteri i ketoni, kao i s aromatskim, alifatskim i kloriranim ugljikovodicima.
\n Trenutno je u pripremi obvezuju\u0107a grani\u010dna vrijednost izlo\u017eenosti na radu za cijelu EU. <\/p>\n

Opasnosti koje se mogu pojaviti<\/h2>\n

Kratkotrajna izlo\u017eenost 1,2-DCP-u kod ljudi mo\u017ee uzrokovati iritaciju, kao i disfunkciju jetre i bubrega nakon oralne i dermalne apsorpcije. Pri vrlo visokim koncentracijama zabilje\u017eena je depresija sredi\u0161njeg \u017eiv\u010danog sustava.
\n Kod dugotrajne izlo\u017eenosti, najkriti\u010dniji u\u010dinak kod ljudi je karcinogenost, posebno pojava tumora \u017eu\u010dnih vodova (kolangiokarcinom). <\/p>\n

\u0160to mo\u017eete u\u010diniti<\/h2>\n

Na radnom mjestu, naju\u010dinkovitiji na\u010din sprje\u010davanja izlo\u017eenosti je zamjena 1,2-DCP-a. Tamo gdje zamjena nije mogu\u0107a i upotreba 1,2-DCP-a se ne mo\u017ee izbje\u0107i, moraju se poduzeti mjere za smanjenje izlo\u017eenosti.
\n Naju\u010dinkovitiji na\u010din izbjegavanja izlo\u017eenosti 1,2-DCP-u je razvoj i kori\u0161tenje zatvorenih sustava. Tamo gdje to nije mogu\u0107e, treba provesti tehni\u010dke mjere poput u\u010dinkovite lokalne ispu\u0161ne ventilacije, uz dobru op\u0107u ventilaciju radnog mjesta i redovite provjere njihove u\u010dinkovitosti, kako bi se osiguralo da se izlo\u017eenost svede na najmanju mogu\u0107u mjeru koliko je to tehni\u010dki mogu\u0107e. <\/p>\n

Sva proizvodnja 1,2-DPC-a odvija se unutar zatvorenih sustava. Izlo\u017eenost se doga\u0111a kada se ti zatvoreni sustavi otvaraju radi rutinskog odr\u017eavanja, inspekcija ili \u010di\u0161\u0107enja. U tim slu\u010dajevima potrebno je koristiti tehni\u010dke mjere i osobnu za\u0161titnu opremu, uklju\u010duju\u0107i RPE. <\/p>\n

Provedite mjere za osiguranje odgovaraju\u0107e op\u0107e higijene radnog mjesta s redovitim \u010di\u0161\u0107enjem i higijenskim skladi\u0161tenjem. Nakon po\u010detnog mjerenja izlo\u017eenosti za procjenu rizika, provodite periodi\u010dne procjene izlo\u017eenosti kako biste provjerili jesu li va\u0161e tehni\u010dke mjere u\u010dinkovite ili je potrebno poduzeti daljnje radnje. Strogo ograni\u010davanje vremena koje radnici provode u izlo\u017eenom radnom okru\u017eenju (npr. putem smjena) i ograni\u010davanje pristupa tim radnim mjestima va\u017ene su mjere za smanjenje izlo\u017eenosti. Radnici moraju biti svjesni mogu\u0107ih rizika povezanih s zadacima koji uklju\u010duju 1,2-DPC, a poslodavci ih moraju redovito osposobljavati i upu\u0107ivati \u200b\u200bo tome kako sigurno raditi s 1,2-DPC. <\/p>\n

Medicinski zdravstveni nadzor potreban je za radnike izlo\u017eene opasnim tvarima te ih stoga treba poticati da prijave rane simptome poput respiratornih problema ili ko\u017enih alergija.
\n Osim toga, obu\u010dite radnike o va\u017enosti u\u010dinkovite osobne higijene. Osigurajte odgovaraju\u0107e prostorije za pranje i nu\u017edu te radnicima dajte dovoljno vremena za higijenske mjere. <\/p>\n

Osigurati da radnici imaju odgovaraju\u0107u osobnu za\u0161titnu opremu, kao \u0161to su za\u0161titna odje\u0107a i rukavice, ako je potrebno. Osobna za\u0161titna oprema treba se koristiti samo kao krajnja mjera i razmatrati samo privremeno, nakon \u0161to su iscrpljena sva mogu\u0107a tehni\u010dka i organizacijska rje\u0161enja. <\/p>\n

Reference: ECHA, ATSDR 2021<\/em><\/p>\n","protected":false},"template":"","carcinogens":[8573],"class_list":["post-106440","fact","type-fact","status-publish","hentry","carcinogens-12-dikloropropan"],"yoast_head":"\n1,2-dikloropropan - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/hr\/fact\/12-dikloropropan\/\" \/>\n<meta property=\"og:locale\" content=\"hr_HR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"1,2-dikloropropan\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! 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