{"id":106008,"date":"2026-06-18T09:35:45","date_gmt":"2026-06-18T09:35:45","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/approcc-li-jiffoka-fuq-ir-riskju-l-ewwel-metodi-ghall-identifikazzjoni-bikrija-ta-riskji-kimici-godda-u-emergenti\/"},"modified":"2026-06-18T09:35:45","modified_gmt":"2026-06-18T09:35:45","slug":"approcc-li-jiffoka-fuq-ir-riskju-l-ewwel-metodi-ghall-identifikazzjoni-bikrija-ta-riskji-kimici-godda-u-emergenti","status":"publish","type":"post","link":"https:\/\/stopcarcinogensatwork.eu\/mt\/approcc-li-jiffoka-fuq-ir-riskju-l-ewwel-metodi-ghall-identifikazzjoni-bikrija-ta-riskji-kimici-godda-u-emergenti\/","title":{"rendered":"Appro\u010b\u010b li Jiffoka fuq ir-Riskju l-Ewwel: metodi g\u0127all-identifikazzjoni bikrija ta’ riskji kimi\u010bi \u0121odda u emer\u0121enti"},"content":{"rendered":"

Minkejja li\u0121ijiet u regolamenti estensivi mfassla biex jipprevjenu mard relatat max-xog\u0127ol, il-\u0127addiema jkomplu jimirdu min\u0127abba l-esponiment g\u0127al sustanzi perikolu\u017ci. Spjegazzjoni wa\u0127da hija li \u0127afna drabi ma jkunx hemm bi\u017c\u017cejjed informazzjoni dwar sustanza perikolu\u017ca, jew dwar it-tip ta\u2019 xog\u0127ol li jista\u2019 jikkaw\u017ca mard. B\u2019ri\u017cultat ta\u2019 dan, ir-rabta bejn il-mard u x-xog\u0127ol \u0127afna drabi ti\u0121i rikonoxxuta biss wara li xi \u0127add jimrad: appro\u010b\u010b reattiv mag\u0127ruf b\u0127ala l-\u201cappro\u010b\u010b tal-marda l-ewwel\u201d. <\/strong><\/p>\n

Appro\u010b\u010b a\u0127jar huwa li ji\u0121u identifikati sustanzi jew tipi ta\u2019 xog\u0127ol perikolu\u017ci qabel ma n-nies jimirdu: l-\u201cappro\u010b\u010b tar-riskju l-ewwel\u201d. L-Istitut Nazzjonali Olandi\u017c g\u0127as-Sa\u0127\u0127a Pubblika u l-Ambjent (RIVM) \u0121abar \u0127arsa \u0121enerali lejn metodi li jistg\u0127u jg\u0127inu biex wie\u0127ed ibassar jekk sustanza jew tip ta\u2019 xog\u0127ol perikolu\u017ci humiex probabbli li jikkaw\u017caw marda okkupazzjonali. <\/p>\n

Lakuni persistenti fl-g\u0127arfien<\/h2>\n

L-g\u0127arfien dwar l-effetti ta\u2019 \u0127sara ta\u2019 sustanzi perikolu\u017ci u l-esponiment tal-\u0127addiema g\u0127alihom g\u0127adu fih lakuni sinifikanti. Ra\u0121uni ewlenija wa\u0127da hija li l-valutazzjoni tar-riskju tal-bi\u010b\u010ba l-kbira tal-kimi\u010bi hija bba\u017cata fuq testijiet tat-tossi\u010bit\u00e0 orali, filwaqt li l-\u0127addiema huma prin\u010bipalment esposti g\u0127al kimi\u010bi permezz ta\u2019 inalazzjoni jew kuntatt mal-\u0121ilda. Barra minn hekk, xi effetti fuq is-sa\u0127\u0127a jistg\u0127u ma jkunux g\u0127adhom \u0121ew identifikati, u d-dejta dwar l-esponiment tista\u2019 tkun nieqsa jew sottovalutata. <\/p>\n

Metodi li jag\u0127tu prijorit\u00e0 lir-riskju: \u0127arsa \u0121enerali<\/h2>\n

Riskji \u0121odda u emer\u0121enti ta’ kimi\u010bi (NERCs) jistg\u0127u ji\u0121u skoperti fi stadji differenti tal-i\u017cvilupp ta’ sustanza, bl-u\u017cu kemm ta’ appro\u010b\u010bi li jag\u0127tu l-ewwel ir-riskju kif ukoll ta’ appro\u010b\u010bi li jag\u0127tu l-ewwel il-marda. L-appro\u010b\u010b li jag\u0127ti l-ewwel ir-riskju jiffoka fuq kimi\u010bi u materjali li g\u0127adhom prin\u010bipalment fil-fa\u017ci ta’ innovazzjoni jew fil-fa\u017ci bikrija tas-suq. Sinjali dwar perikli potenzjali, kemm g\u0127as-sikurezza kimika kif ukoll g\u0127as-sa\u0127\u0127a okkupazzjonali, jistg\u0127u jin\u0121abru billi ti\u0121i kkombinata d-dejta dwar il-proprjetajiet perikolu\u017ci mad-dejta dwar l-esponiment jew l-u\u017cu potenzjali. <\/p>\n

Diversi istituti ta’ ri\u010berka u a\u0121enziji regolatorji \u017cviluppaw, jew qed ji\u017cviluppaw, metodi li jag\u0127tu l-ewwel lok g\u0127ar-riskju g\u0127ad-detezzjoni bikrija tar-riskju, inklu\u017ci l-Awtorit\u00e0 Ewropea dwar is-Sigurt\u00e0 fl-Ikel (EFSA), l-A\u0121enzija Ewropea g\u0127as-Sustanzi Kimi\u010bi (ECHA), l-A\u0121enzija Ewropea g\u0127as-Sigurt\u00e0 u s-Sa\u0127\u0127a fuq il-Post tax-Xog\u0127ol (EU-OSHA), u l-RIVM. \u0126ar\u0121u metodi addizzjonali minn kollaborazzjonijiet u s\u0127ubijiet. L-RIVM identifikat ukoll appro\u010b\u010bi o\u0127ra li jistg\u0127u jservu b\u0127ala metodi li jag\u0127tu l-ewwel lok g\u0127ar-riskju, b\u0127all-pro\u010bess TICHNER u diversi metodi in silico g\u0127ad-detezzjoni bikrija tat-tossi\u010bit\u00e0 kimika. <\/p>\n

Il-\u0127arsa \u0121enerali turi li kull metodu jservi skop differenti, u li l-ammont ta\u2019 xog\u0127ol involut kif ukoll l-informazzjoni me\u0127tie\u0121a jvarjaw konsiderevolment minn metodu g\u0127al ie\u0127or.<\/p>\n

Lejn aktar \u017cvilupp<\/h2>\n

L-RIVM ivvaluta l-metodi identifikati li jag\u0127tu l-ewwel ir-riskju kontra sett ta\u2019 kriterji biex jiddetermina l-idoneit\u00e0 tag\u0127hom g\u0127at-tis\u0127i\u0127 tal-appro\u010b\u010b li jag\u0127ti l-ewwel ir-riskju. L-aktar metodi promettenti huma appro\u010b\u010bi b\u2019rendiment g\u0127oli li ju\u017caw databases kbar u jikkombinaw dejta dwar il-periklu u l-esponiment. Madankollu, l-ebda metodu wie\u0127ed ma jissodisfa l-kriterji kollha, u kull metodu xorta je\u0127tie\u0121 \u0121udizzju espert g\u0127all-prijoritizzazzjoni u s-segwitu. Abba\u017ci ta\u2019 din il-valutazzjoni, intg\u0127a\u017clu \u017cew\u0121 metodi g\u0127al aktar \u017cvilupp: l-g\u0127odod ta\u2019 tbassir Lexces in silico u s-sett ta\u2019 g\u0127odod RIVM Endocrine Disruptor. Dan ix-xog\u0127ol jikkontribwixxi g\u0127al appro\u010b\u010b aktar preventiv g\u0127all-kan\u010bers okkupazzjonali. <\/p>\n