{"id":108389,"date":"2026-06-29T10:02:28","date_gmt":"2026-06-29T10:02:28","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/12-dikloropropan\/"},"modified":"2026-06-29T10:02:28","modified_gmt":"2026-06-29T10:02:28","slug":"12-dikloropropan","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/sl\/fact\/12-dikloropropan\/","title":{"rendered":"1,2-dikloropropan"},"content":{"rendered":"

V EU ni na voljo ocen trenutnega \u0161tevila zaposlenih, ki so izpostavljeni 1,2-dikloropropanu (1,2-DPC). Vdihavanje velja za glavno pot exposure, vendar so zaposleni lahko izpostavljeni tudi prek stika s ko\u017eo.<\/p><\/blockquote>\n

1,2-DPC je razvr\u0161\u010den kot rakotvorne snovi kategorije 1B (v skladu z Uredbo o razvr\u0161\u010danju, ozna\u010devanju in pakiranju), kar pomeni, da se na podlagi dokazov na \u017eivalih domneva, da ima rakotvorni potencial za ljudi.<\/p>\n

Toksi\u010dni u\u010dinki so vklju\u010devali po\u0161kodbe jeter in ledvic, intravaskularno koagulacijo, hemoliti\u010dno anemijo ter razli\u010dne simptome osrednjega \u017eiv\u010dnega sistema.<\/p>\n

Kje se pojavljajo tveganja<\/h2>\n

1,2-DCP je stranski produkt, ki nastaja v znatnih koli\u010dinah med proizvodnim procesom propilen oksida po klorohidrinskem postopku za proizvodnjo epiklorohidrina. 1,2-DCP se je v preteklosti uporabljal kot fumigant za tla, kot kemijski intermediat ter kot industrijsko topilo. Najden je bil v odstranjevalcih barv, lakih in sredstvih za odstranjevanje premazov s pohi\u0161tva. Kot fumigant za tla se ne uporablja ve\u010d.<\/p>\n

Trenutno je njegova glavna uporaba kot intermediat pri proizvodnji perkloroetilena in drugih kloriranih kemikalij.
\nNa splo\u0161no je exposure na delovnem mestu videti omejena, saj se snov obravnava v strogo nadzorovanih pogojih. Glavna dejavnost, pri kateri je exposure mo\u017ena, je ro\u010dno vzdr\u017eevanje ali \u010di\u0161\u010denje.<\/p>\n

Ve\u010d o snovi<\/h2>\n

V \u010disti obliki je 1,2-DPC brezbarvna, vnetljiva, teko\u010da in mobilna teko\u010dina z vonjem po kloroformu. Me\u0161a se z ve\u010dino organskih topil, kot so alkoholi, estri in ketoni, pa tudi z aromatskimi, alifatskimi in kloriranimi ogljikovodiki.
\nZavezujo\u010da mejna vrednost poklicne exposure za celotno EU je trenutno v pripravi.<\/p>\n

Nevarnosti, ki se lahko pojavijo<\/h2>\n

Kratkotrajna exposure 1,2-DCP pri ljudeh lahko povzro\u010di dra\u017eenje ter motnje delovanja jeter in ledvic po oralni in dermalni absorpciji. Pri zelo visokih koncentracijah so poro\u010dali o depresiji osrednjega \u017eiv\u010dnega sistema.
\nPri dolgotrajni exposure je najpomembnej\u0161i u\u010dinek pri ljudeh rakotvornost, zlasti pojav tumorjev \u017eol\u010dnih vodov (holangiokarcinom).<\/p>\n

Kaj lahko naredi\u0161<\/h2>\n

Na delovnem mestu je naju\u010dinkovitej\u0161i na\u010din za prepre\u010devanje exposure zamenjava 1,2-DCP. Kadar zamenjava ni mogo\u010da in se uporabi 1,2-DCP ni mogo\u010de izogniti, je treba sprejeti ukrepe za zmanj\u0161anje exposure.
\nNaju\u010dinkovitej\u0161i na\u010din za izogibanje exposure 1,2-DCP je razvoj in uporaba zaprtih sistemov. Kadar to ni mogo\u010de, je treba uvesti tehni\u010dne ukrepe, kot je u\u010dinkovito lokalno odsesovanje, dopolnjeno z dobrim splo\u0161nim prezra\u010devanjem delovnega mesta in rednimi preverjanji njihove u\u010dinkovitosti, da se exposure zmanj\u0161a, kolikor je tehni\u010dno mogo\u010de.<\/p>\n

Celotna proizvodnja 1,2-DPC poteka v zaprtih sistemih. Exposure nastane, ko se ti zaprti sistemi odprejo za rutinsko vzdr\u017eevanje, preglede ali \u010di\u0161\u010denje. V teh primerih je treba uporabiti tehni\u010dne ukrepe in osebno varovalno opremo, vklju\u010dno z varovalno opremo za dihala.<\/p>\n

Uvedi ukrepe za zagotavljanje ustrezne splo\u0161ne higiene na delovnem mestu z rednim \u010di\u0161\u010denjem in higienskim shranjevanjem. Po za\u010detni meritvi exposure za ocena tveganja izvajaj periodi\u010dne ocene exposure, da preveri\u0161, ali so uvedeni tehni\u010dni ukrepi u\u010dinkoviti ali pa so potrebni dodatni ukrepi. Strogo omejevanje \u010dasa, ki ga zaposleni pre\u017eivijo v izpostavljenem delovnem okolju (npr. z izmenami), in omejevanje dostopa do teh delovnih mest sta pomembna ukrepa za zmanj\u0161anje exposure. Zaposleni morajo biti seznanjeni z mo\u017enimi tveganji, povezanimi z nalogami, ki vklju\u010dujejo 1,2-DPC, delodajalci pa jih morajo redno usposabljati in jim dajati navodila, kako varno delati z 1,2-DPC.<\/p>\n

Za zaposlene, izpostavljene nevarnim snovem, je potreben zdravstveni nadzor, zato jih je treba spodbujati, da zgodaj poro\u010dajo o simptomih, kot so te\u017eave z dihanjem ali ko\u017ene alergije.
\nPoleg tega zaposlene usposobi o pomenu u\u010dinkovite osebne higiene. Zagotovi ustrezne umivalnice in sanitarije ter zaposlenim omogo\u010di dovolj \u010dasa za higienske ukrepe.<\/p>\n

Poskrbi, da imajo zaposleni po potrebi ustrezno osebno varovalno opremo, kot so za\u0161\u010ditna obla\u010dila in rokavice. Osebna varovalna oprema naj se uporablja le kot zadnja mo\u017enost in le za\u010dasno, potem ko so iz\u010drpane mo\u017ene tehni\u010dne in organizacijske re\u0161itve.<\/p>\n

Viri: ECHA, ATSDR 2021<\/em><\/p>\n","protected":false},"template":"","carcinogens":[8718],"class_list":["post-108389","fact","type-fact","status-publish","hentry","carcinogens-12-dikloropropan"],"yoast_head":"\n1,2-dikloropropan - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/sl\/fact\/12-dikloropropan\/\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"1,2-dikloropropan\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! 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