{"id":108426,"date":"2026-06-29T09:56:12","date_gmt":"2026-06-29T09:56:12","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/123-trikloropropan\/"},"modified":"2026-06-29T09:56:12","modified_gmt":"2026-06-29T09:56:12","slug":"123-trikloropropan","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/sl\/fact\/123-trikloropropan\/","title":{"rendered":"1,2,3-trikloropropan"},"content":{"rendered":"

Ocene trenutnega \u0161tevila zaposlenih, izpostavljenih 1,2,3-triklorpropanu (1,2,3-TPC) v EU, niso na voljo. Vdihavanje velja za primarno pot izpostavljenosti, \u010deprav so lahko zaposleni izpostavljeni tudi prek stika s ko\u017eo.<\/p><\/blockquote>\n

1,2,3-TPC je razvr\u0161\u010den kot rakotvorna snov kategorije 1B (v skladu z uredbo o razvr\u0161\u010danju, ozna\u010devanju in pakiranju), kar pomeni, da se domneva, da ima rakotvorni potencial za ljudi na podlagi dokazov pri \u017eivalih.<\/p>\n

Na voljo ni podatkov o ljudeh, ki bi dokazovali, da 1,2,3-TCP povzro\u010da raka pri ljudeh. \u0160tudije na \u017eivalih ka\u017eejo, da lahko dolgotrajna izpostavljenost tej snovi povzro\u010di tumorje na ve\u010d mestih, kot so ustna votlina in predzobec.<\/p>\n

Kje se pojavljajo tveganja<\/h2>\n

Primarna uporaba 1,2,3-TPC je kot monomer pri proizvodnji polimerov ali kot vmesni produkt pri proizvodnji drugih snovi (pesticidi, 2,3-diklorpropen, polisulfidi in heksafluoropropilen). 1,2,3-TCP lahko ostane kot ne\u010disto\u010da v nekaterih od teh kemikalij. 1,2,3-TCP se proizvaja v znatnih koli\u010dinah kot stranski produkt pri proizvodnji epiklorhidrina, ko se klor doda alil kloridu. Ta proces poteka v zaprtih sistemih.
\nNa splo\u0161no se zdi, da je izpostavljenost na delovnem mestu omejena zaradi ravnanja v strogo nadzorovanih pogojih. Glavna dejavnost, pri kateri je izpostavljenost mogo\u010da, je med ro\u010dnimi vzdr\u017eevalnimi ali \u010distilnimi dejavnostmi.<\/p>\n

Ve\u010d o snovi<\/h2>\n

V svoji \u010disti obliki je 1,2,3-TPC brezbarvna do rumena teko\u010dina z omejeno topnostjo v vodi, mo\u010dnim vonjem po kloroformu, zmerno hlapnostjo in visoko vnetljivostjo. Gre za umetno kemikalijo, prisotno v okolju kot posledica antropogene dejavnosti.
\nZavezujo\u010da mejna vrednost poklicne izpostavljenosti v celotni EU je trenutno v pripravi.<\/p>\n

Nevarnosti, ki se lahko pojavijo<\/h2>\n

Podatki o akutni strupenosti pri ljudeh so omejeni na majhno \u0161tevilo poro\u010dil o primerih, ki opisujejo predvsem u\u010dinke na jetra in nevrolo\u0161ke u\u010dinke po visoki, vendar na splo\u0161no ne dobro kvantificirani oralni ali inhalacijski izpostavljenosti. Najpomembnej\u0161i zdravstveni u\u010dinek kroni\u010dne izpostavljenosti 1,2,3-TCP je rakotvornost. Pri ljudeh ni podatkov na voljo. Pri poskusnih \u017eivalih 1,2,3-TCP povzro\u010da tumorje na ve\u010d mestih in z visoko incidenco tako pri mi\u0161ih kot pri podganah. Ker je metabolizem 1,2,3-TCP kvalitativno podoben v \u010dlove\u0161kih in glodavskih mikrosomih, se \u0161teje, da je verjetno rakotvoren za ljudi.<\/p>\n

Kaj lahko naredi\u0161<\/h2>\n

Na delovnem mestu je naju\u010dinkovitej\u0161i na\u010din prepre\u010devanja izpostavljenosti zamenjava 1,2,3-TCP. Kjer zamenjava ni mogo\u010da in uporabe 1,2,3-TCP ni mogo\u010de prepre\u010diti, je treba sprejeti ukrepe za zmanj\u0161anje izpostavljenosti.<\/p>\n

Naju\u010dinkovitej\u0161i na\u010din izogibanja izpostavljenosti 1,2,3-TCP je razvoj in uporaba zaprtih sistemov. Kjer to ni mogo\u010de, je treba izvajati tehni\u010dne ukrepe, kot so u\u010dinkovito lokalno odsesavanje, dopolnjeno z dobrim splo\u0161nim prezra\u010devanjem delovnega mesta in rednimi pregledi njihove u\u010dinkovitosti, da se zagotovi, da je izpostavljenost \u010dim bolj zmanj\u0161ana, kolikor je tehni\u010dno mogo\u010de.<\/p>\n

Izvajaj redne ocene izpostavljenosti, da preveri\u0161, ali so va\u0161i za\u0161\u010ditni ukrepi u\u010dinkoviti ali pa je potrebno sprejeti dodatne ukrepe. Zaposleni se morajo zavedati u\u010dinkov izpostavljenosti in jih je treba redno usposabljati o nadzornih ukrepih, potrebnih za varno delo z 1,2,3-TCP, da se prepre\u010di izpostavljenost. Priporo\u010dljivo je vklju\u010diti poklicnega zdravnika.<\/p>\n

Zagotovi, da imajo zaposleni ustrezno osebno varovalno opremo, kot so za\u0161\u010ditna obla\u010dila in rokavice, \u010de je potrebno. Osebne varovalne opreme ne sme uporabljati kot edini preventivni ukrep. Pred tem je treba izvesti \u010dim ve\u010d zgoraj navedenih tehni\u010dnih in organizacijskih ukrepov. Poskrbi, da se uporablja prava osebna varovalna oprema, kot so za\u0161\u010dita za o\u010di in obraz, rokavice, za\u0161\u010ditna obla\u010dila in za\u0161\u010dita dihal. Poleg tega je treba pri izbiri opreme upo\u0161tevati anatomijo zaposlenih, ki jo bodo uporabljali, in v primeru za\u0161\u010ditne opreme za dihala, ki temelji na prilagajanju obrazu, je zelo priporo\u010dljivo izvesti preizkus prileganja pri vsaki osebi. Poleg tega je treba vse zaposlene pou\u010diti, naj si pred odmorom ali vstopom v drugo obmo\u010dje pravilno umijejo roke ter naj se na koncu vsake izmene umijejo in preoble\u010dejo.<\/p>\n

Osebno varovalno opremo je treba uporabljati le kot zadnjo mo\u017enost in jo upo\u0161tevati le za\u010dasno, potem ko so iz\u010drpane mo\u017ene tehni\u010dne re\u0161itve.<\/p>\n

Reference: ECHA<\/em><\/p>\n","protected":false},"template":"","carcinogens":[8717],"class_list":["post-108426","fact","type-fact","status-publish","hentry","carcinogens-123-trikloropropan"],"yoast_head":"\n1,2,3-trikloropropan - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/sl\/fact\/123-trikloropropan\/\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"1,2,3-trikloropropan\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! 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