{"id":106569,"date":"2026-06-29T09:56:12","date_gmt":"2026-06-29T09:56:12","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/123-trikloropropan\/"},"modified":"2026-06-29T09:56:12","modified_gmt":"2026-06-29T09:56:12","slug":"123-trikloropropan","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/","title":{"rendered":"1,2,3-Trikloropropan"},"content":{"rendered":"

AB\u2019de 1,2,3-Trikloropropan\u2019a (1,2,3-TPC) maruz kalan \u00e7al\u0131\u015fanlar\u0131n mevcut say\u0131s\u0131na ili\u015fkin tahminler mevcut de\u011fildir. Soluma, birincil exposure yolu olarak kabul edilmekle birlikte, \u00e7al\u0131\u015fanlar deri yoluyla da maruz kalabilirler. <\/p><\/blockquote>\n

1,2,3-TPC, (S\u0131n\u0131fland\u0131rma, Etiketleme ve Ambalajlama Y\u00f6netmeli\u011fi\u2019ne g\u00f6re) Carcinogen Kategori 1B olarak s\u0131n\u0131fland\u0131r\u0131lm\u0131\u015ft\u0131r; bu, hayvanlar \u00fczerinde yap\u0131lan ara\u015ft\u0131rmalara dayanarak, bu maddenin insanlar i\u00e7in kanserojen potansiyele sahip oldu\u011fu varsay\u0131ld\u0131\u011f\u0131 anlam\u0131na gelir.<\/p>\n

1,2,3-TCP\u2019nin insanlarda kansere yol a\u00e7\u0131p a\u00e7mad\u0131\u011f\u0131na dair insan verisi mevcut de\u011fildir. Hayvanlar \u00fczerinde yap\u0131lan ara\u015ft\u0131rmalar, bu maddeye uzun s\u00fcre exposure\u2019\u0131n a\u011f\u0131z bo\u015flu\u011fu ve \u00f6n mide gibi \u00e7e\u015fitli b\u00f6lgelerde t\u00fcm\u00f6rlere yol a\u00e7abilece\u011fini g\u00f6stermektedir. <\/p>\n

Risklerin olu\u015ftu\u011fu yerler<\/h2>\n

1,2,3-TPC\u2019nin ba\u015fl\u0131ca kullan\u0131m alan\u0131, polimer \u00fcretiminde monomer olarak veya di\u011fer maddelerin (Pestisitler, 2,3-dikloropropen, polis\u00fclf\u00fcrler ve heksafloropropilen) \u00fcretiminde ara madde olarak kullan\u0131lmas\u0131d\u0131r. 1,2,3-TCP, bu kimyasallar\u0131n baz\u0131lar\u0131nda bir safs\u0131zl\u0131k olarak kalabilir. 1,2,3-TCP, alil klor\u00fcre klor eklendi\u011finde Epiklorohidrin \u00fcretimi s\u0131ras\u0131nda \u00f6nemli miktarlarda bir yan \u00fcr\u00fcn olarak \u00fcretilir. Bu i\u015flem kapal\u0131 sistemlerde ger\u00e7ekle\u015fir.
\nGenel olarak, i\u015fyerinde exposure, s\u0131k\u0131 bir \u015fekilde kontrol edilen ko\u015fullar alt\u0131nda ger\u00e7ekle\u015ftirilen i\u015flemler nedeniyle s\u0131n\u0131rl\u0131 g\u00f6r\u00fcnmektedir. Exposure’un m\u00fcmk\u00fcn oldu\u011fu ba\u015fl\u0131ca faaliyetler, manuel bak\u0131m veya temizlik faaliyetleri s\u0131ras\u0131nda ger\u00e7ekle\u015fmektedir. <\/p>\n

Madde hakk\u0131nda daha fazla bilgi<\/h2>\n

Saf haliyle 1,2,3-TPC, suda s\u0131n\u0131rl\u0131 \u00e7\u00f6z\u00fcn\u00fcrl\u00fc\u011fe sahip, kloroform benzeri g\u00fc\u00e7l\u00fc bir kokusu olan, orta derecede u\u00e7uculu\u011fa ve y\u00fcksek yan\u0131c\u0131l\u0131\u011fa sahip, renksiz ila sar\u0131 renkli bir s\u0131v\u0131d\u0131r. Bu, insan yap\u0131m\u0131 bir kimyasald\u0131r ve antropojenik faaliyetlerin bir sonucu olarak \u00e7evrede bulunur.
\nAB \u00e7ap\u0131nda ba\u011flay\u0131c\u0131 bir mesleki exposure s\u0131n\u0131r de\u011feri \u015fu anda haz\u0131rlanmaktad\u0131r. <\/p>\n

Olu\u015fabilecek tehlikeler<\/h2>\n

\u0130nsanlarda akut toksisite verileri, y\u00fcksek d\u00fczeyde (ancak genellikle nicel olarak iyi belirlenmemi\u015f) oral veya solunum yoluyla exposure\u2019\u0131n ard\u0131ndan ortaya \u00e7\u0131kan, esas olarak karaci\u011fer ve n\u00f6rolojik etkileri tan\u0131mlayan az say\u0131da vaka rapar\u0131yla s\u0131n\u0131rl\u0131d\u0131r. 1,2,3-TCP\u2019ye kronik exposure\u2019\u0131n en \u00f6nemli sa\u011fl\u0131k etkisi carcinogenliktir. \u0130nsanlarda bu konuda veri bulunmamaktad\u0131r. Deney hayvanlar\u0131nda 1,2,3-TCP, hem farelerde hem de s\u0131\u00e7anlarda bir\u00e7ok b\u00f6lgede ve y\u00fcksek s\u0131kl\u0131kta t\u00fcm\u00f6rlere yol a\u00e7maktad\u0131r. 1,2,3-TCP’nin metabolizmas\u0131 insan ve kemirgen mikrozomlar\u0131nda niteliksel olarak benzer oldu\u011fundan, bu maddenin insanlar i\u00e7in carcinogen olmas\u0131 muhtemel kabul edilmektedir. <\/p>\n

Yapabilecekleriniz<\/h2>\n

\u0130\u015fyerinde exposure\u2019\u0131 \u00f6nlemenin en etkili yolu, 1,2,3-TCP\u2019nin ba\u015fka bir maddeyle ikame edilmesidir. \u0130kame imk\u00e2n\u0131 bulunmad\u0131\u011f\u0131nda ve 1,2,3-TCP\u2019nin kullan\u0131m\u0131ndan ka\u00e7\u0131n\u0131lamad\u0131\u011f\u0131nda, exposure\u2019\u0131 azaltmaya y\u00f6nelik \u00f6nlemler al\u0131nmal\u0131d\u0131r. <\/p>\n

1,2,3-TCP’ye maruz kalmay\u0131 \u00f6nlemenin en etkili yolu, kapal\u0131 sistemler geli\u015ftirmek ve kullanmakt\u0131r. Bunun m\u00fcmk\u00fcn olmad\u0131\u011f\u0131 durumlarda, exposure’un teknik olarak m\u00fcmk\u00fcn oldu\u011funca en aza indirilmesini sa\u011flamak i\u00e7in, etkili yerel egzoz havaland\u0131rmas\u0131 gibi teknik \u00f6nlemler al\u0131nmal\u0131 ve bu \u00f6nlemler, iyi bir genel i\u015fyeri havaland\u0131rmas\u0131 ile desteklenmeli ve etkinlikleri d\u00fczenli olarak kontrol edilmelidir. <\/p>\n

Mevcut koruyucu \u00f6nlemlerinizin etkili olup olmad\u0131\u011f\u0131n\u0131 veya ilave \u00f6nlemlerin al\u0131nmas\u0131 gerekip gerekmedi\u011fini kontrol etmek i\u00e7in d\u00fczenli exposure de\u011ferlendirmeleri ger\u00e7ekle\u015ftirin. \u00c7al\u0131\u015fanlar, exposure’un etkilerinin fark\u0131nda olmal\u0131 ve exposure’u \u00f6nlemek amac\u0131yla 1,2,3-TCP ile g\u00fcvenli bir \u015fekilde \u00e7al\u0131\u015fmak i\u00e7in gerekli kontrol \u00f6nlemleri konusunda d\u00fczenli olarak e\u011fitilmelidir. Bir i\u015f sa\u011fl\u0131\u011f\u0131 hekiminin s\u00fcrece dahil edilmesi tavsiye edilir. <\/p>\n

Gerekirse, \u00e7al\u0131\u015fanlar\u0131n koruyucu giysi ve eldiven gibi uygun ki\u015fisel koruma donan\u0131m\u0131na sahip oldu\u011fundan emin olun. Ki\u015fisel koruma donan\u0131m\u0131, tek \u00f6nleyici tedbir olarak kullan\u0131lmamal\u0131d\u0131r. Yukar\u0131da belirtilen teknik ve organizasyonel \u00f6nlemlerin m\u00fcmk\u00fcn oldu\u011funca \u00e7o\u011fu \u00f6nceden uygulanm\u0131\u015f olmal\u0131d\u0131r. G\u00f6z ve y\u00fcz korumas\u0131, eldiven, koruyucu giysi ve solunum korumas\u0131 gibi do\u011fru ki\u015fisel koruma ekipmanlar\u0131n\u0131n kullan\u0131ld\u0131\u011f\u0131ndan emin olun. Ayr\u0131ca, ekipman se\u00e7erken, onu kullanacak \u00e7al\u0131\u015fanlar\u0131n anatomisi dikkate al\u0131nmal\u0131 ve y\u00fcze g\u00f6re ayarlanan solunum koruyucu ekipmanlar s\u00f6z konusu oldu\u011funda, her ki\u015fi i\u00e7in bir uyum testi yap\u0131lmas\u0131 \u015fiddetle tavsiye edilir. Ayr\u0131ca, t\u00fcm \u00e7al\u0131\u015fanlara mola vermeden veya ba\u015fka bir alana girmeden \u00f6nce ellerini d\u00fczg\u00fcn bir \u015fekilde y\u0131kamalar\u0131 ve her vardiya sonunda kendilerini y\u0131kamalar\u0131 ve k\u0131yafetlerini de\u011fi\u015ftirmeleri konusunda talimat verilmelidir. <\/p>\n

Ki\u015fisel koruma donan\u0131m\u0131, ancak son \u00e7are olarak ve olas\u0131 teknik \u00e7\u00f6z\u00fcmlerin t\u00fcm\u00fc denenmi\u015f olduktan sonra ge\u00e7ici bir \u00f6nlem olarak kullan\u0131lmal\u0131d\u0131r.<\/p>\n

Kaynaklar: ECHA<\/em><\/p>\n","protected":false},"template":"","carcinogens":[8671],"class_list":["post-106569","fact","type-fact","status-publish","hentry","carcinogens-123-trikloropropan"],"yoast_head":"\n1,2,3-Trikloropropan - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"1,2,3-Trikloropropan\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/\" \/>\n<meta property=\"og:site_name\" content=\"STOP carcinogens at work\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/fact\\\/123-trikloropropan\\\/\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/fact\\\/123-trikloropropan\\\/\",\"name\":\"1,2,3-Trikloropropan - STOP carcinogens at work\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/#website\"},\"datePublished\":\"2026-06-29T09:56:12+00:00\",\"description\":\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/fact\\\/123-trikloropropan\\\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/fact\\\/123-trikloropropan\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/fact\\\/123-trikloropropan\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Facts\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/fact\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"T\u00fcm kanserojenler\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/carcinogens\\\/tum-kanserojenler\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"1,2,3-Trikloropropan\",\"item\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/carcinogens\\\/123-trikloropropan\\\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"1,2,3-Trikloropropan\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/#website\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/\",\"name\":\"STOP Carcinogens at work\",\"description\":\"Every year, about 100.000 people die from cancer that was caused by exposure to carcinogens at work in Europe.\",\"publisher\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/#organization\"},\"alternateName\":\"Roadmap on Carcinogens\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"tr\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/#organization\",\"name\":\"TNO\",\"alternateName\":\"This is a European wide voluntary action scheme\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/cropped-FavLarge-1.png\",\"contentUrl\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/wp-content\\\/uploads\\\/2024\\\/08\\\/cropped-FavLarge-1.png\",\"width\":512,\"height\":512,\"caption\":\"TNO\"},\"image\":{\"@id\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/tr\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"publishingPrinciples\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/homepage\\\/legal\\\/\",\"ownershipFundingInfo\":\"https:\\\/\\\/stopcarcinogensatwork.eu\\\/general\\\/about-us\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"1,2,3-Trikloropropan - STOP carcinogens at work","description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/","og_locale":"tr_TR","og_type":"article","og_title":"1,2,3-Trikloropropan","og_description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","og_url":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/","og_site_name":"STOP carcinogens at work","twitter_card":"summary_large_image","twitter_misc":{"Tahmini okuma s\u00fcresi":"4 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/","url":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/","name":"1,2,3-Trikloropropan - STOP carcinogens at work","isPartOf":{"@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/#website"},"datePublished":"2026-06-29T09:56:12+00:00","description":"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.","breadcrumb":{"@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/123-trikloropropan\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/stopcarcinogensatwork.eu\/tr\/"},{"@type":"ListItem","position":2,"name":"Facts","item":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/"},{"@type":"ListItem","position":3,"name":"T\u00fcm kanserojenler","item":"https:\/\/stopcarcinogensatwork.eu\/tr\/carcinogens\/tum-kanserojenler\/"},{"@type":"ListItem","position":4,"name":"1,2,3-Trikloropropan","item":"https:\/\/stopcarcinogensatwork.eu\/tr\/carcinogens\/123-trikloropropan\/"},{"@type":"ListItem","position":5,"name":"1,2,3-Trikloropropan"}]},{"@type":"WebSite","@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/#website","url":"https:\/\/stopcarcinogensatwork.eu\/tr\/","name":"STOP Carcinogens at work","description":"Every year, about 100.000 people die from cancer that was caused by exposure to carcinogens at work in Europe.","publisher":{"@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/#organization"},"alternateName":"Roadmap on Carcinogens","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/stopcarcinogensatwork.eu\/tr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"tr"},{"@type":"Organization","@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/#organization","name":"TNO","alternateName":"This is a European wide voluntary action scheme","url":"https:\/\/stopcarcinogensatwork.eu\/tr\/","logo":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/#\/schema\/logo\/image\/","url":"https:\/\/stopcarcinogensatwork.eu\/wp-content\/uploads\/2024\/08\/cropped-FavLarge-1.png","contentUrl":"https:\/\/stopcarcinogensatwork.eu\/wp-content\/uploads\/2024\/08\/cropped-FavLarge-1.png","width":512,"height":512,"caption":"TNO"},"image":{"@id":"https:\/\/stopcarcinogensatwork.eu\/tr\/#\/schema\/logo\/image\/"},"publishingPrinciples":"https:\/\/stopcarcinogensatwork.eu\/homepage\/legal\/","ownershipFundingInfo":"https:\/\/stopcarcinogensatwork.eu\/general\/about-us\/"}]}},"_links":{"self":[{"href":"https:\/\/stopcarcinogensatwork.eu\/tr\/wp-json\/wp\/v2\/fact\/106569","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stopcarcinogensatwork.eu\/tr\/wp-json\/wp\/v2\/fact"}],"about":[{"href":"https:\/\/stopcarcinogensatwork.eu\/tr\/wp-json\/wp\/v2\/types\/fact"}],"wp:attachment":[{"href":"https:\/\/stopcarcinogensatwork.eu\/tr\/wp-json\/wp\/v2\/media?parent=106569"}],"wp:term":[{"taxonomy":"carcinogens","embeddable":true,"href":"https:\/\/stopcarcinogensatwork.eu\/tr\/wp-json\/wp\/v2\/carcinogens?post=106569"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}