{"id":57907,"date":"2023-08-29T10:09:24","date_gmt":"2023-08-29T10:09:24","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/epiklorohidrin\/"},"modified":"2025-06-13T13:25:47","modified_gmt":"2025-06-13T13:25:47","slug":"epiklorohidrin","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/epiklorohidrin\/","title":{"rendered":"Epiklorohidrin"},"content":{"rendered":"

AB \u201cde Epiklorohidrin (1-kloro-2,3-epoksipropan) maddesine maruz kalan en son tahmini i\u015f\u00e7i say\u0131s\u0131 2011 y\u0131l\u0131 itibariyle yakla\u015f\u0131k 44.000\u201d dir. Soluma birincil maruziyet yolu olarak kabul edilir, ancak i\u015f\u00e7iler deri temas\u0131 yoluyla da maruz kalabilirler. Epiklorohidrin Kanserojen Kategori 1B olarak s\u0131n\u0131fland\u0131r\u0131lm\u0131\u015ft\u0131r ( S\u0131n\u0131fland\u0131rma, Etiketleme ve Ambalajlama y\u00f6netmeli\u011fine g\u00f6re), bu da hayvan testlerindeki kan\u0131tlara dayanarak insanlar i\u00e7in kanserojen potansiyele sahip oldu\u011fu varsay\u0131ld\u0131\u011f\u0131 anlam\u0131na gelir. Epiklorohidrine maruz kalma, akci\u011fer kanseri ve merkezi sinir sistemi t\u00fcm\u00f6rlerinin ortaya \u00e7\u0131kmas\u0131yla ili\u015fkilidir. <\/p><\/blockquote>\n

Risklerin olu\u015ftu\u011fu yerler<\/h2>\n

Epiklorohidrin mesleki maruziyet, klordan \u00fcretimi s\u0131ras\u0131nda ve kaplamalarda, yap\u0131\u015ft\u0131r\u0131c\u0131larda ve plastiklerde kullan\u0131lan epoksi re\u00e7inelerin \u00fcretiminde meydana gelebilir. Epoksi re\u00e7ineler boya, yap\u0131\u015ft\u0131r\u0131c\u0131, otomotiv, havac\u0131l\u0131k end\u00fcstrisi, in\u015faat, yenilenebilir enerji ekipmanlar\u0131 ve elektronik (bask\u0131l\u0131 devre kartlar\u0131 i\u00e7in ve elektronik bile\u015fenleri hasardan korumak amac\u0131yla kaps\u00fcllemek i\u00e7in kullan\u0131l\u0131r) gibi end\u00fcstriyel sekt\u00f6rlerde \u00e7e\u015fitli uygulamalara sahiptir. Epiklorohidrin ayr\u0131ca su ar\u0131tma i\u00e7in \u00f6zel re\u00e7ineler ve polimerlerde, ka\u011f\u0131t end\u00fcstrisi i\u00e7in y\u00fcksek \u0131slak mukavemetli re\u00e7inelerde veya hava ve suyu ar\u0131tmak i\u00e7in iyon de\u011fi\u015fimi yoluyla kullan\u0131l\u0131r. Buna ek olarak, sel\u00fcloz esterleri ve eterleri i\u00e7in \u00e7\u00f6z\u00fcc\u00fc olarak, y\u00fcn ve pamu\u011fun i\u015flenmesinde ve kau\u00e7uk i\u015flemlerinde kullan\u0131l\u0131r. Ayr\u0131ca, maruz kalma riski olan meslekler aras\u0131nda sert poli\u00fcretan k\u00f6p\u00fcklerin \u00fcretimi i\u00e7in poliollerin kimyasal sentez tesislerinde \u00e7al\u0131\u015fanlar ve y\u0131kama \u00fcr\u00fcnleri i\u00e7in y\u00fczey aktif maddeler bulunmaktad\u0131r. <\/p>\n

Madde hakk\u0131nda daha fazla bilgi<\/h2>\n

Epiklorohidrin keskin, sar\u0131msak benzeri bir kokuya sahip renksiz yan\u0131c\u0131 bir s\u0131v\u0131d\u0131r, suda orta derecede \u00e7\u00f6z\u00fcn\u00fcr, ancak \u00e7o\u011fu polar organik \u00e7\u00f6z\u00fcc\u00fc ile kar\u0131\u015fabilir. Yanma s\u0131ras\u0131nda zehirli ve a\u015f\u0131nd\u0131r\u0131c\u0131 hidrojen klor\u00fcr ve klor dumanlar\u0131 olu\u015fturur. Epiklorohidrin al\u00fcminyum, \u00e7inko, alkoller, fenoller, aminler ve organik asitlerle \u015fiddetli reaksiyona girer; bu da yang\u0131n ve patlama tehlikesi olu\u015fturur. <\/p>\n

Olu\u015fabilecek tehlikeler<\/h2>\n

Epiklorohidrin buhar\u0131n\u0131n solunmas\u0131 birincil maruziyet yolu olarak kabul edilir, ancak cilt yoluyla da \u00f6nemli miktarda al\u0131m m\u00fcmk\u00fcnd\u00fcr. Epiklorohidrin k\u0131sa s\u00fcreli maruziyet g\u00f6zlerde, solunum yollar\u0131nda ve ciltte tahri\u015fe neden olabilir. Buhar\u0131n solunmas\u0131 ast\u0131m benzeri reaksiyonlara neden olabilir. Ayr\u0131ca, epiklorohidrin ile temas cildi ve g\u00f6zleri tahri\u015f edebilir ve yakabilir. Y\u00fcksek maruziyet seviyelerinde bulant\u0131, kusma, \u00f6ks\u00fcr\u00fck, nefes darl\u0131\u011f\u0131, akci\u011fer iltihab\u0131, akci\u011fer \u00f6demi, merkezi sinir sistemi etkileri ve b\u00f6brek ve karaci\u011fer hasar\u0131 g\u00f6r\u00fclebilir. Epiklorohidrin ile tekrarlanan veya uzun s\u00fcreli temas ciltte hassasiyete neden olabilir. Ayr\u0131ca, Epiklorohidrin kronik maruziyetin b\u00f6brekler, karaci\u011fer ve akci\u011ferler \u00fczerinde etkilerinin yan\u0131 s\u0131ra lenfatik ve hemopoetik kanser riskinde art\u0131\u015fa neden olabilir. <\/p>\n

Yapabilecekleriniz<\/h2>\n

Maruziyeti \u00f6nlemenin en etkili yolu epiklorohidrinin ikame edilmesidir, \u00f6rne\u011fin epoksi re\u00e7inelerin \u00fcretimi i\u00e7in alternatif y\u00f6ntemler; kaplamalar, in\u015faat, yap\u0131\u015ft\u0131r\u0131c\u0131lar, laminatlar ve kompozitler gibi farkl\u0131 uygulamalarda epoksi re\u00e7inelerin ikame edilmesi; gliserin sentezi i\u00e7in alternatif i\u015flemler; ve epiklorohidrin elastomerlerin ikame edilmesi. Epiklorohidrinin ikamesinin m\u00fcmk\u00fcn olmad\u0131\u011f\u0131 ve epiklorohidrin kullan\u0131m\u0131ndan ka\u00e7\u0131n\u0131lamad\u0131\u011f\u0131 durumlarda, maruziyeti azaltacak \u00f6nlemler al\u0131nmal\u0131d\u0131r. <\/p>\n

Epiklorodrine maruz kalmay\u0131 \u00f6nlemenin en etkili yolu kapal\u0131 sistemler geli\u015ftirmek ve kullanmakt\u0131r. Bunun m\u00fcmk\u00fcn olmad\u0131\u011f\u0131 durumlarda, maruziyetin teknik olarak m\u00fcmk\u00fcn oldu\u011funca en aza indirilmesini sa\u011flamak i\u00e7in i\u015fyerinin iyi havaland\u0131r\u0131lmas\u0131yla desteklenen etkili yerel egzoz havaland\u0131rmas\u0131 gibi teknik \u00f6nlemler uygulanmal\u0131 ve bunlar\u0131n etkinli\u011fi kontrol edilmelidir. <\/p>\n

Uygulad\u0131\u011f\u0131n\u0131z koruyucu \u00f6nlemlerin etkili olup olmad\u0131\u011f\u0131n\u0131 veya ba\u015fka \u00f6nlemlerin al\u0131nmas\u0131 gerekip gerekmedi\u011fini kontrol etmek i\u00e7in d\u00fczenli maruziyet de\u011ferlendirmeleri uygulay\u0131n. \u00c7al\u0131\u015fanlar maruziyetin etkilerinin fark\u0131nda olmal\u0131 ve maruziyeti \u00f6nlemek i\u00e7in epiklorohidrin ile g\u00fcvenli bir \u015fekilde \u00e7al\u0131\u015fmak i\u00e7in gerekli kontrol \u00f6nlemleri konusunda d\u00fczenli olarak e\u011fitilmelidir. Bir i\u015fyeri hekiminin dahil edilmesi tavsiye edilir. \u00c7al\u0131\u015fanlar\u0131 erken belirtileri bildirmeleri i\u00e7in te\u015fvik edin. Ayr\u0131ca, t\u00fcm \u00e7al\u0131\u015fanlara mola vermeden veya ba\u015fka bir alana girmeden \u00f6nce ellerini d\u00fczg\u00fcn bir \u015fekilde y\u0131kamalar\u0131 ve her vardiya sonunda kendilerini y\u0131kamalar\u0131 ve k\u0131yafetlerini de\u011fi\u015ftirmeleri talimat\u0131 verilmelidir. <\/p>\n

\u00c7al\u0131\u015fanlar\u0131n gerekirse koruyucu giysi ve eldiven gibi yeterli ki\u015fisel koruyucu ekipmana sahip oldu\u011fundan emin olun. Ki\u015fisel koruyucu ekipman tek \u00f6nleyici tedbir olarak kullan\u0131lmamal\u0131d\u0131r. Yukar\u0131daki teknik ve organizasyonel \u00f6nlemlerin m\u00fcmk\u00fcn oldu\u011funca \u00e7o\u011fu \u00f6nceden uygulanm\u0131\u015f olmal\u0131d\u0131r. Ayr\u0131ca, ekipman se\u00e7erken, ekipman\u0131 kullanacak i\u015f\u00e7ilerin anatomisi dikkate al\u0131nmal\u0131 ve y\u00fcz ayar\u0131na dayal\u0131 solunum koruyucu ekipman s\u00f6z konusu oldu\u011funda, her ki\u015fi \u00fczerinde bir uyum testi yap\u0131lmas\u0131 \u015fiddetle tavsiye edilir. <\/p>\n

Ki\u015fisel koruyucu ekipman sadece son \u00e7are olarak kullan\u0131lmal\u0131 ve olas\u0131 teknik \u00e7\u00f6z\u00fcmler t\u00fcketildikten sonra sadece ge\u00e7ici olarak d\u00fc\u015f\u00fcn\u00fclmelidir. \u0130\u015f\u00e7iler KKD’nin do\u011fru kullan\u0131m\u0131 ve bak\u0131m\u0131 i\u00e7in gerekli e\u011fitim ve bilgileri almal\u0131d\u0131r. <\/p>\n

Referanslar: ECHA, S\u0131n\u0131fland\u0131rma, Etiketleme ve Ambalajlama, IARC, ICSCs, IOM<\/em><\/p>\n","protected":false},"template":"","carcinogens":[2527],"class_list":["post-57907","fact","type-fact","status-publish","hentry","carcinogens-epiklorohidrin"],"yoast_head":"\nEpiklorohidrin - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/epiklorohidrin\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Epiklorohidrin\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! 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