{"id":57907,"date":"2023-08-29T10:09:24","date_gmt":"2023-08-29T10:09:24","guid":{"rendered":"https:\/\/stopcarcinogensatwork.eu\/fact\/epiklorohidrin\/"},"modified":"2026-06-13T11:31:49","modified_gmt":"2026-06-13T11:31:49","slug":"epiklorohidrin","status":"publish","type":"fact","link":"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/epiklorohidrin\/","title":{"rendered":"Epiklorohidrin"},"content":{"rendered":"

2011 y\u0131l\u0131na ait en son tahminlere g\u00f6re, AB\u2019de Epiklorohidrin (1-kloro-2,3-epoksipropan) ile kar\u015f\u0131la\u015fan \u00e7al\u0131\u015fan say\u0131s\u0131 yakla\u015f\u0131k 44.000\u2019dir. Soluma, exposure\u2019un ba\u015fl\u0131ca yolu olarak kabul edilmekle birlikte, \u00e7al\u0131\u015fanlar deri temas\u0131 yoluyla da exposure\u2019a maruz kalabilirler. Epiklorohidrin, Karcinogen Kategori 1B (S\u0131n\u0131fland\u0131rma, Etiketleme ve Ambalajlama y\u00f6netmeli\u011fine g\u00f6re) olarak s\u0131n\u0131fland\u0131r\u0131lm\u0131\u015ft\u0131r; bu, hayvanlar \u00fczerinde yap\u0131lan testlerdeki kan\u0131tlara dayanarak, insanlar i\u00e7in kanserojen potansiyeli oldu\u011fu varsay\u0131ld\u0131\u011f\u0131 anlam\u0131na gelir. Epiklorohidrine exposure, akci\u011fer kanseri ve merkezi sinir sistemi t\u00fcm\u00f6rlerinin ortaya \u00e7\u0131kmas\u0131yla ili\u015fkilidir. <\/p><\/blockquote>\n

Risklerin olu\u015ftu\u011fu yerler<\/h2>\n

Epiklorohidrin maruz kalma, klordan \u00fcretimi s\u0131ras\u0131nda oldu\u011fu kadar, kaplama, yap\u0131\u015ft\u0131r\u0131c\u0131 ve plastiklerde kullan\u0131lan epoksi re\u00e7inelerinin \u00fcretiminde de meydana gelebilir. Epoksi re\u00e7ineleri, boya, yap\u0131\u015ft\u0131r\u0131c\u0131, otomotiv, havac\u0131l\u0131k ve uzay end\u00fcstrisi, \u0130n\u015faat, yenilenebilir enerji ekipmanlar\u0131 ve elektronik gibi end\u00fcstriyel sekt\u00f6rlerde \u00e7e\u015fitli uygulamalara sahiptir (bask\u0131l\u0131 devre kartlar\u0131nda ve elektronik bile\u015fenleri hasardan korumak i\u00e7in kaps\u00fcllemek amac\u0131yla kullan\u0131l\u0131r). Epiklorohidrin ayr\u0131ca su ar\u0131t\u0131m\u0131 i\u00e7in \u00f6zel re\u00e7ineler ve polimerlerde, ka\u011f\u0131t end\u00fcstrisi i\u00e7in y\u00fcksek \u0131slak mukavemetli re\u00e7inelerde veya hava ve suyu ar\u0131tmak i\u00e7in iyon de\u011fi\u015fimi yoluyla kullan\u0131l\u0131r. Buna ek olarak, sel\u00fcloz esterleri ve eterleri i\u00e7in bir \u00e7\u00f6z\u00fcc\u00fc olarak, y\u00fcn ve pamu\u011fun i\u015flenmesinde ve kau\u00e7uk i\u015flemlerinde kullan\u0131l\u0131r. Ayr\u0131ca, exposure riski ta\u015f\u0131yan meslekler aras\u0131nda, sert poli\u00fcretan k\u00f6p\u00fcklerin \u00fcretimi i\u00e7in poliollerin kimyasal sentez tesislerinde \u00e7al\u0131\u015fanlar ve y\u0131kama \u00fcr\u00fcnleri i\u00e7in y\u00fczey aktif maddeler bulunmaktad\u0131r. <\/p>\n

Madde hakk\u0131nda daha fazla bilgi<\/h2>\n

Epiklorohidrin, keskin, sar\u0131msak benzeri bir kokuya sahip, renksiz ve yan\u0131c\u0131 bir s\u0131v\u0131d\u0131r; suda orta derecede \u00e7\u00f6z\u00fcn\u00fcr, ancak \u00e7o\u011fu polar organik \u00e7\u00f6z\u00fcc\u00fcyle kar\u0131\u015fabilir. Yanma s\u0131ras\u0131nda, hidrojen klor\u00fcr ve klordan olu\u015fan zehirli ve a\u015f\u0131nd\u0131r\u0131c\u0131 dumanlar ortaya \u00e7\u0131kar. Epiklorohidrin, al\u00fcminyum, \u00e7inko, alkoller, fenoller, aminler ve organik asitlerle \u015fiddetli reaksiyona girer; bu da yang\u0131n ve patlama tehlikesi yarat\u0131r. <\/p>\n

AB taraf\u0131ndan 1,9 mg\/m\u00b3 (Zaman A\u011f\u0131rl\u0131kl\u0131 Ortalama) olarak belirlenen ba\u011flay\u0131c\u0131 bir mesleki exposure s\u0131n\u0131r\u0131 y\u00fcr\u00fcrl\u00fcktedir.<\/p>\n

Olu\u015fabilecek tehlikeler<\/h2>\n

Epiklorohidrin buhar\u0131n\u0131n solunmas\u0131, exposureun ba\u015fl\u0131ca yolu olarak kabul edilir; ancak deri yoluyla da \u00f6nemli \u00f6l\u00e7\u00fcde emilim m\u00fcmk\u00fcnd\u00fcr. Epiklorohidrine k\u0131sa s\u00fcreli exposure, g\u00f6zlerde, solunum yollar\u0131nda ve deride tahri\u015fe neden olabilir. Buhar\u0131n solunmas\u0131 ast\u0131m benzeri reaksiyonlara neden olabilir. Ayr\u0131ca, Epiklorohidrin ile temas ciltte ve g\u00f6zlerde tahri\u015fe ve yan\u0131\u011fa neden olabilir. Y\u00fcksek d\u00fczeyde exposure durumunda mide bulant\u0131s\u0131, kusma, \u00f6ks\u00fcr\u00fck, nefes darl\u0131\u011f\u0131, akci\u011fer iltihab\u0131, pulmoner \u00f6dem, merkezi sinir sistemi etkileri ile b\u00f6brek ve karaci\u011fer hasar\u0131 g\u00f6zlemlenebilir. Epiklorohidrin ile tekrarlanan veya uzun s\u00fcreli temas, ciltte hassasiyete neden olabilir. Ayr\u0131ca, epiklorohidrine kronik exposure, b\u00f6brekler, karaci\u011fer ve akci\u011ferler \u00fczerinde etkiler yaratabilece\u011fi gibi, lenfatik ve hematopoietik kanser riskini de art\u0131rabilir. <\/p>\n

Yapabilecekleriniz<\/h2>\n

Maruziyeti \u00f6nlemenin en etkili yolu, Epiklorohidrin yerine alternatif y\u00f6ntemler kullanmakt\u0131r; \u00f6rne\u011fin epoksi re\u00e7inelerinin \u00fcretiminde alternatif y\u00f6ntemler; kaplama, \u0130n\u015faat, yap\u0131\u015ft\u0131r\u0131c\u0131lar, laminatlar ve kompozitler gibi \u00e7e\u015fitli uygulamalarda epoksi re\u00e7inelerinin ikameleri; gliserin sentezi i\u00e7in alternatif s\u00fcre\u00e7ler; ve Epiklorohidrin elastomerleri i\u00e7in ikame maddeler. Epiklorohidrin ikamesinin m\u00fcmk\u00fcn olmad\u0131\u011f\u0131 ve Epiklorohidrin kullan\u0131m\u0131n\u0131n ka\u00e7\u0131n\u0131lmaz oldu\u011fu durumlarda, exposure’\u0131 azaltmaya y\u00f6nelik \u00f6nlemler al\u0131nmal\u0131d\u0131r. <\/p>\n

Epiklorodrine maruz kalmay\u0131 \u00f6nlemenin en etkili yolu, kapal\u0131 sistemler geli\u015ftirmek ve kullanmakt\u0131r. Bunun m\u00fcmk\u00fcn olmad\u0131\u011f\u0131 durumlarda, exposure’un teknik olarak m\u00fcmk\u00fcn oldu\u011funca en aza indirilmesini sa\u011flamak i\u00e7in, etkili yerel egzoz havaland\u0131rmas\u0131 gibi teknik \u00f6nlemler al\u0131nmal\u0131, bu \u00f6nlemler i\u015fyerinin iyi bir \u015fekilde havaland\u0131r\u0131lmas\u0131yla desteklenmeli ve bunlar\u0131n etkinli\u011fi kontrol edilmelidir. <\/p>\n

Mevcut koruyucu \u00f6nlemlerinizin etkili olup olmad\u0131\u011f\u0131n\u0131 veya ilave \u00f6nlemlerin al\u0131nmas\u0131 gerekip gerekmedi\u011fini kontrol etmek i\u00e7in d\u00fczenli exposure de\u011ferlendirmeleri yap\u0131n. \u00c7al\u0131\u015fanlar, exposure’un etkilerinin fark\u0131nda olmal\u0131 ve exposure’u \u00f6nlemek amac\u0131yla epiklorohidrin ile g\u00fcvenli bir \u015fekilde \u00e7al\u0131\u015fmak i\u00e7in gerekli kontrol \u00f6nlemleri konusunda d\u00fczenli olarak e\u011fitilmelidir. Bir i\u015f sa\u011fl\u0131\u011f\u0131 hekiminin s\u00fcrece dahil edilmesi tavsiye edilir. \u00c7al\u0131\u015fanlar\u0131 erken belirtileri bildirmeleri konusunda te\u015fvik edin. Ayr\u0131ca, t\u00fcm \u00e7al\u0131\u015fanlara mola vermeden veya ba\u015fka bir alana girmeden \u00f6nce ellerini d\u00fczg\u00fcn bir \u015fekilde y\u0131kamalar\u0131 ve her vardiya sonunda kendilerini y\u0131kamalar\u0131 ve k\u0131yafetlerini de\u011fi\u015ftirmeleri konusunda talimat verilmelidir. <\/p>\n

Gerekirse, \u00e7al\u0131\u015fanlar\u0131n koruyucu giysi ve eldiven gibi uygun ki\u015fisel koruyucu donan\u0131ma sahip olmalar\u0131n\u0131 sa\u011flay\u0131n. Ki\u015fisel koruma donan\u0131m\u0131, tek \u00f6nleyici tedbir olarak kullan\u0131lmamal\u0131d\u0131r. Yukar\u0131daki teknik ve organizasyonel \u00f6nlemlerin m\u00fcmk\u00fcn oldu\u011funca \u00e7o\u011fu \u00f6nceden uygulanm\u0131\u015f olmal\u0131d\u0131r. Ayr\u0131ca, ekipman se\u00e7erken, onu kullanacak \u00e7al\u0131\u015fanlar\u0131n anatomisi dikkate al\u0131nmal\u0131 ve y\u00fcze g\u00f6re ayarlanan solunum koruyucu ekipman s\u00f6z konusu oldu\u011funda, her ki\u015fi i\u00e7in bir uyum testi yap\u0131lmas\u0131 \u015fiddetle tavsiye edilir. <\/p>\n

Ki\u015fisel koruma donan\u0131m\u0131, ancak son \u00e7are olarak ve olas\u0131 teknik \u00e7\u00f6z\u00fcmlerin t\u00fcm\u00fc denenmi\u015f olduktan sonra ge\u00e7ici bir \u00f6nlem olarak kullan\u0131lmal\u0131d\u0131r. \u00c7al\u0131\u015fanlara, ki\u015fisel koruma donan\u0131m\u0131n do\u011fru kullan\u0131m\u0131 ve bak\u0131m\u0131 konusunda gerekli e\u011fitim ve bilgiler verilmelidir. <\/p>\n

Kaynaklar: ECHA, S\u0131n\u0131fland\u0131rma, Etiketleme ve Ambalajlama, IARC, ICSCs, IOM<\/em><\/p>\n","protected":false},"template":"","carcinogens":[2527],"class_list":["post-57907","fact","type-fact","status-publish","hentry","carcinogens-epiklorohidrin"],"yoast_head":"\nEpiklorohidrin - STOP carcinogens at work<\/title>\n<meta name=\"description\" content=\"Be aware of what you work with! We collected all the important information these causing substances in easy-to-understand factsheets.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopcarcinogensatwork.eu\/tr\/fact\/epiklorohidrin\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Epiklorohidrin\" \/>\n<meta property=\"og:description\" content=\"Be aware of what you work with! 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