The facts on 4,4′-Methylenedianiline (MDA)

Last update September 3, 2024

This factsheet is under development. Only limited information is available.

Possible substitutions

Restrictions on the use of azo dyes that can be broken down into carcinogenic aromatic amines - TRGS 614 (DE)

Factsheets for identifying and substituting carcinogens

The “Fiches d’Aide au Répérage des Cancérogènes” (FAR) and the “Fiches d’Aide à la Substitution des Cancérogènes” (FAS) have been created by the French Prevention Network (Prevention Departments of Occupational health and pension insurance funds – the CARSATs- and INRS). These factsheets, compiled by OSH and technology experts, are short...

Possible measures

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Please note that this substance or some of it's compounds are listed in Annex XIV (REACH regulation). This substance some of it's compounds are only allowed to be used, imported, or brought into the market, if authorisation requirements of REACH are fulfilled.

Occupations involved

Application Engineer

Chemical Plant Operators

Color Chemist

Laboratory Technicians

Machinist

Materials scientist

Metal Fabricator

Metal finisher

Metal machinist

Plastics engineer

Research and development (R&D) engineer and scientist

Sheet metal worker

Tool and die maker

ECHA registration

CAS number 101-77-9

EC number 202-974-4

Annex VI of CLP 1B

Number of registrations (2023) 10

Tonnage band registred (2023) 1.000 t/y [4], 10-100 t/y [2], 1-10 t/y [1]

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GESTIS Database

The data pool may be used for the purpose of occupational health and safety or to obtain information on the hazards posed by chemical substances.

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General facts

Facts about cancer-causing agents:

The direct costs of carcinogen exposure at work across Europe are estimated at 2.4 billion Euros per year.
Every year, about 120.000 persons get cancer from exposure to carcinogens at work
Every year, almost 100.000 people die from cancer that was caused by exposure at work
Annually more than 100.000 people die because of work-related cancer.

The facts on 4,4′-Methylenedianiline (MDA)

The facts on 4,4′-Methylenedianiline (MDA)

Possible substitutions

Possible measures

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