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Enzymatic processes versus chemical processes in the preparation of 6-aminopenicillanic acid

Enzymatic processes versus chemical processes in the preparation of 6-aminopenicillanic acid

Type of measure: Substitution

Using enzymatic processes instead of chemical processes may result in substitution of hazardous substances.

How?

Fewer steps during synthesis and low solvent use are the major benefits. Energy savings, fewer safety and disposal issues, and improved product quality also lead to cost benefits.

Published July 26, 2023
Please note that this substance or some of it's compounds are listed in Annex XIV (REACH regulation). This substance some of it's compounds are only allowed to be used, imported, or brought into the market, if authorisation requirements of REACH are fulfilled.
Please be aware that for this carcinogen you need to be more cautious when determining potential skin contact and how to regard dermal exposure in your risk reduction strategy.
Relevance
Carcinogens involved:
Dichloromethane
About this case
For more information please contact:
SUBSPORTplus Team
General facts

Facts about cancer-causing agents:

  • The direct costs of carcinogen exposure at work across Europe are estimated at 2.4 billion Euros per year.
  • Every year, about 120.000 persons get cancer from exposure to carcinogens at work
  • Annually more than 100.000 people die because of work-related cancer.