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The facts on Isoprene

The facts on Isoprene

Last update December 5, 2024

Limit values

EU

Unknown, but national limits might apply.

Read all national directives

Austria

EU directive

Belgium

EU directive

Bulgaria

EU directive

Croatia

EU directive

National directive

Czech Republic

EU directive

Cyprus

EU directive

Denmark

EU directive

Estonia

EU directive

Finland

EU directive

France

EU directive

Germany

80,4 mg/m³ (TWA)
67,2 mg/m³ short term

National directive

Greece

EU directive

Hungary

EU directive

National directive

Iceland

EU directive

National directive

Ireland

EU directive

Italy

EU directive

Latvia

40 mg/m³ (TWA)

Lithuania

EU directive

National directive

Luxembourg

EU directive

National directive

Malta

EU directive

Netherlands

EU directive

North Macedonia

EU directive

Norway

EU directive

National directive

Poland

EU directive

National directive

Portugal

EU directive

National directive

Romania

EU directive

Serbia

EU directive

Slovakia

EU directive

Slovenia

EU directive

National directive

Spain

EU directive

National directive

Sweden

EU directive

National directive

Turkey

EU directive

References: cancer.gov, EFSA, IARC, EC, NIOSH, OSHA, CAREX

Possible substitutions

Guidance for Employers’ obligations of the substitution of carcinogenic substances

The Guidance The Netherlands Labour Authority have developed a comprehensive document tailored to provide employers or inspectorates guidance on how to interpret the extent of the obligations to search for alternatives for using carcinogenic substances. This resource offers a step-by-step plan, consisting of 3 diagrams, which describe 3 different situations:...

Factsheets for identifying and substituting carcinogens

The “Fiches d’Aide au Répérage des Cancérogènes” (FAR) and the “Fiches d’Aide à la Substitution des Cancérogènes” (FAS) have been created by the French Prevention Network (Prevention Departments of Occupational health and pension insurance funds – the CARSATs- and INRS). These factsheets, compiled by OSH and technology experts, are short...

Work environment carcinogens: what should an employee know?

The Estonian National Institute for Health Development published this guide about carcinogens in different work environments and work areas. What are possible effects of working with carcinogens, which measures should be taken for workers to be working safely and how should the health of exposed workers be monitored? The guide...

Possible measures

Trade union campaign in Belgium to prevent occupational cancers

Belgium Statistics – Work Related Cancer In Belgium, around 1,800 people die every year from work-related cancer. This figure, which is largely underestimated, illustrates an alarming reality that receives little...

Creating Control Guidance Sheets (CGSs)

Control Guidance Sheets (CGSs) are essential tools designed to help employers manage and mitigate the risks associated with exposure to carcinogenic substances in the workplace. These documents serve as practical...

Managing the risks of carcinogens in the workplace through an educational game

True to the motto ‘You can’t teach an old dog new tricks’ it is necessary to start with integrating activities that raise awareness in primary schools and in vocational educational...

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Occupations involved

Catalyst Scientists and Researchers

Chemical Engineers and Chemists

Chemical Technicians

Chemists and Chemical Technicians

Cosmetic Chemist

Dentists

Fragrance Chemist

Machine Operators

Medical and Dental Practice Managers

Medical Laboratory Technicians

Packaging and Logistics Personnel

Painter and coater

Pharmaceutical chemist

Pharmaceutical engineer

Pharmacist

Process operators

Production line operators

Production operators

Production supervisor

Research and development (R&D) engineer and scientist

Retread technician

Rubber technologist

Welder and fabricator

Welders

ECHA registration

CAS number 78-79-5

EC number 201-143-3

Annex VI of CLP 1B

Number of registrations (2023) 78

Tonnage band registred (2023) ≥ 100.000 to < 1.000.000

The European Chemicals Agency (ECHA) works for the safe use of chemicals. It implements the EU’s groundbreaking chemicals legislation, benefiting human health, the environment and innovation and competitiveness in Europe.

View ECHA Profile

View ECHA Substance Infocard

GESTIS Database

The data pool may be used for the purpose of occupational health and safety or to obtain information on the hazards posed by chemical substances.

Go to GESTIS Substance

General facts

Facts about cancer-causing agents:

The direct costs of carcinogen exposure at work across Europe are estimated at 2.4 billion Euros per year.
Every year, about 120.000 persons get cancer from exposure to carcinogens at work
Annually more than 100.000 people die because of work-related cancer.